New Insight into the Role of Adenosine in Demyelination, Stroke and Neuropathic Pain

被引：11
作者：
Coppi, Elisabetta [1 ]
Dettori, Ilaria [1 ]
Cherchi, Federica [1 ]
Bulli, Irene [1 ]
Venturini, Martina [1 ]
Pedata, Felicita [1 ]
Pugliese, Anna Maria [1 ]
机构：
[1] Univ Florence, Dept Neurosci Psychol Drug Res & Child Hlth NEURO, Sect Pharmacol & Toxicol, Florence, Italy
来源：
FRONTIERS IN PHARMACOLOGY | 2021年 / 11卷
关键词：
cerebral ischemia; oxygen-glucose deprivation; adenosine receptors; oligodendrocyte differentiation; neuropathic pain; dorsal root ganglion neurons; neuroinflammation; GLUCOSE DEPRIVATION; CELL-DIFFERENTIATION; RECEPTOR AGONIST; SYNAPTIC-TRANSMISSION; BRAIN-DAMAGE; K+ CURRENTS; A(2B); ANTAGONIST; ACTIVATION; MIGRATION;
D O I：
10.3389/fphar.2020.625662
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页数：5
相关论文
共 44 条
[1]   The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2B receptor [J].
Betti, Marco ;
Catarzi, Daniela ;
Varano, Flavia ;
Falsini, Matteo ;
Varani, Katia ;
Vincenzi, Fabrizio ;
Ben Diego, Dal ;
Lambertucci, Catia ;
Colotta, Vittoria .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 150 :127-139
[2]   Purinergic signalling during development and ageing [J].
Burnstock, Geoffrey ;
Dale, Nicholas .
PURINERGIC SIGNALLING, 2015, 11 (03) :277-305
[3]  
Cherchi F., 2020, NEURAL REGEN RES, V9, P155, DOI [10.3389/fncel.2015.00155, DOI 10.3389/FNCEL.2015.00155]
[4]   3-Hydroxy-1H-quinazoline-2,4-dione derivatives as new antagonists at ionotropic glutamate receptors: Molecular modeling and pharmacological studies [J].
Colotta, Vittoria ;
Lenzi, Ombretta ;
Catarzi, Daniela ;
Varano, Flavia ;
Squarcialupi, Lucia ;
Costagli, Chiara ;
Galli, Alessandro ;
Ghelardini, Carla ;
Pugliese, Anna Maria ;
Maraula, Giovanna ;
Coppi, Elisabetta ;
Pellegrini-Giampietro, Domenico E. ;
Pedata, Felicita ;
Sabbadin, Davide ;
Moro, Stefano .
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 54 :470-482
[5]   P2Y1 receptor modulation of Ca2+-activated K+ currents in medium-sized neurons from neonatal rat striatal slices [J].
Coppi, E. ;
Pedata, F. ;
Gibb, A. J. .
JOURNAL OF NEUROPHYSIOLOGY, 2012, 107 (03) :1009-1021
[6]   Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices [J].
Coppi, Elisabetta ;
Pugliese, Anna Maria ;
Stephan, Holger ;
Mueller, Christa E. ;
Pedata, Felicita .
PURINERGIC SIGNALLING, 2007, 3 (03) :203-219
[7]   ATP modulates cell proliferation and elicits two different electrophysiological responses in human mesenchymal stem cells [J].
Coppi, Elisabetta ;
Pugliese, Anna Maria ;
Urbani, Serena ;
Melani, Alessia ;
Cerbai, Elisabetta ;
Mazzanti, Benedetta ;
Bosi, Alberto ;
Saccardi, Riccardo ;
Pedata, Felicita .
STEM CELLS, 2007, 25 (07) :1840-1849
[8]   A2B Adenosine Receptors: When Outsiders May Become an Attractive Target to Treat Brain Ischemia or Demyelination [J].
Coppi, Elisabetta ;
Dettori, Ilaria ;
Cherchi, Federica ;
Bulli, Irene ;
Venturini, Martina ;
Lana, Daniele ;
Giovannini, Maria Grazia ;
Pedata, Felicita ;
Pugliese, Anna Maria .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 21 (24) :1-14
[9]   Adenosine A2B receptors inhibit K+ currents and cell differentiation in cultured oligodendrocyte precursor cells and modulate sphingosine-1-phosphate signaling pathway [J].
Coppi, Elisabetta ;
Cherchi, Federica ;
Fusco, Irene ;
Dettori, Ilaria ;
Gaviano, Lisa ;
Magni, Giada ;
Catarzi, Daniela ;
Colotta, Vittoria ;
Varano, Flavia ;
Rossi, Francesca ;
Bernacchioni, Caterina ;
Donati, Chiara ;
Bruni, Paola ;
Pedata, Felicita ;
Cencetti, Francesca ;
Pugliese, Anna Maria .
BIOCHEMICAL PHARMACOLOGY, 2020, 177
[10]   Adenosine A3 receptor activation inhibits pronociceptive N-type Ca2+ currents and cell excitability in dorsal root ganglion neurons [J].
Coppi, Elisabetta ;
Cherchi, Federica ;
Fusco, Irene ;
Failli, Paola ;
Vona, Alessia ;
Dettori, Ilaria ;
Gaviano, Lisa ;
Lucarini, Elena ;
Jacobson, Kenneth A. ;
Tosh, Dilip K. ;
Salvemini, Daniela ;
Ghelardini, Carla ;
Pedata, Felicita ;
Mannelli, Lorenzo Di Cesare ;
Pugliese, Anna Maria .
PAIN, 2019, 160 (05) :1103-1118
12345