Diagnosis and Management of Cutaneous B-Cell Lymphomas

被引:12
作者
Malachowski, Stephen J. [1 ]
Sun, James [2 ]
Chen, Pei-Ling [2 ]
Seminario-Vidal, Lucia [1 ,2 ]
机构
[1] Univ S Florida, Morsani Coll Med, Dept Dermatol & Cutaneous Surg, 12901 Bruce B Downs Blvd,MDC 79, Tampa, FL 33612 USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Dept Cutaneous Oncol, 10920 McKinley Dr, Tampa, FL 33612 USA
关键词
B-cell lymphoma; Cutaneous marginal zone lymphoma; Cutaneous follicle center lymphoma; Cutaneous diffuse large B-cell lymphoma; Intravascular diffuse large B-cell lymphoma; WHO-EORTC CLASSIFICATION; BCL-2 PROTEIN EXPRESSION; TREATMENT-OF-CANCER; PROGNOSTIC-FACTORS; EUROPEAN-ORGANIZATION; LEG TYPE; CLINICOPATHOLOGICAL FEATURES; DIFFERENTIAL-DIAGNOSIS; INTERFERON-GAMMA; RITUXIMAB;
D O I
10.1016/j.det.2019.05.004
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Primary cutaneous B-cell lymphomas are a group of diseases with indolent and aggressive behavior. The goal of the initial workup is to evaluate for systemic involvement, provide adequate staging, and guide therapy. Histopathological studies are a critical part of the workup for classification of these lymphomas because they are similar to their nodal counterparts. There are limited data for treatment guidelines, and thus, therapy differs among institutions. Overall, localized therapies are preferred for indolent types and chemotherapy or immunotherapy for the aggressive forms.
引用
收藏
页码:443 / +
页数:13
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