Associated Risk of Malignancy in Patients with Cardiovascular Disease: Evidence and Possible Mechanism

被引：34
作者：
Hasin, Tal [1 ]
Iakobishvili, Zaza [2 ]
Weisz, Giora [1 ]
机构：
[1] Shaare Zedek Med Ctr, Dept Cardiol, 12 Byeth St,POB 3235, IL-9103102 Jerusalem, Israel
[2] Rabin Med Ctr, Dept Cardiol, Petah Tiqwa, Israel
来源：
AMERICAN JOURNAL OF MEDICINE | 2017年 / 130卷 / 07期
关键词：
Cardiovascular; Causality; Heart failure; Malignancy; Risk factors; HYPOXIA-INDUCIBLE FACTOR-1; ENDOTHELIAL GROWTH-FACTOR; HIPPO PATHWAY; VENOUS THROMBOEMBOLISM; INCREASED EXPRESSION; IONIZING-RADIATION; THROMBIN RECEPTOR; HEART-FAILURE; TUMOR-CELLS; IN-VITRO;
D O I：
10.1016/j.amjmed.2017.02.024
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Cardiovascular disease and malignancy are leading causes of morbidity and mortality. Increased risk of malignancy was identified in patients with cardiovascular disease, including patients with heart failure, heart failure after myocardial infarction, patients undergoing cardiac intervention, and patients after a thrombotic event. Common risk factors and biological pathways can explain this association and are explored in this review. Further research is needed to establish the causes of malignancy in this population and direct possible intervention. (C) 2017 Elsevier Inc. All rights reserved.
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收藏
页码：780 / 785
页数：6
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