Outcome of Different Regimes of Antibiotics Used in patients with Acute Cholecystitis Secondary to Gall Stones according to severity of disease

Aim: To assess the amendments in surgeons' practice of antibiotics used in the patients with cholecystitis secondary to gall stones according to severity of disease. Methodology: After the approval of hospital ethical committee of the hospital. This descriptive study was done at Divisional Head Quarter Teaching Hospital, Mirpur Azad Kashmir. It was consisted on 300 hundred patients who presented in 2017 & 2019 and fulfill the inclusion criteria with gall stones. Written informed consent taken from every patients. The major variables included patients' demographics data, antibiotics used for surgical results. Results: In this study 300 patients were included. The mean age of patients was 48.8 +/- 13.2 years. There were 154(51%) female and 146 (49%) patients were male. The mean age was 49.8 +/- 13.2 years. The severe cholecystitis patients received (> grade II), 12(41.4%) had ASA level of >2, compared to 12(8.5%) and 41(22.2%) of patients in mild and moderate acute cholecystitis respectively. Conclusion: It is concluded that Tokyo Guidelines not only greatly influenced but also standardized the choice of antibiotics in patients without compromising the infective and surgical outcomes.