Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract

被引：50

作者：

Amant, DCS ^{[1
]}

Valentin-Bon, IE ^{[1
]}

Jerse, AE ^{[1
]}

机构：

[1] Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, F Edward Hebert Sch Med, Bethesda, MD 20814 USA

来源：

INFECTION AND IMMUNITY | 2002年 / 70卷 / 12期

关键词：

D O I：

10.1128/IAI.70.12.7169-7171.2002

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Epidemiological studies suggest H2O2-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H2O2 is the primary mediator of inhibition.

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页码：7169 / 7171

页数：3

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