Palladium catalyzed addition of carbon pronucleophiles to conjugated enynes

被引：21
|
作者：
Gevorgyan, V
Kadowaki, C
Salter, MM
Kadota, I
Saito, S
Yamamoto, Y
机构：
[1] TOHOKU UNIV,GRAD SCH SCI,DEPT CHEM,SENDAI,MIYAGI 98077,JAPAN
[2] TOHOKU UNIV,INST CHEM REACT SCI,RES CTR ORGAN RESOURCES & MAT CHEM,SENDAI,MIYAGI 98077,JAPAN
来源：
TETRAHEDRON | 1997年 / 53卷 / 27期
关键词：
D O I：
10.1016/S0040-4020(97)00602-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Palladium catalyzed addition of certain carbon pronucleophiles 2 to conjugated enynes 1 afforded the corresponding allenes 3 in good to excellent yields. The most reactive methynes such as methylmalononitrile 2c enabled to undergo double addition leading to alkenes 4. Catalyst optimization supported Pd-2(dba)(3) . CHC3 - dppf combination as the best system among all catalysts tested. The plausible mechanisms for these catalytic reactions were proposed. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：9097 / 9106
页数：10
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