Siderophore-mediated iron acquisition in the staphylococci

被引:60
作者
Beasley, Federico C. [1 ]
Heinrichs, David E. [1 ]
机构
[1] Univ Western Ontario, Dept Microbiol & Immunol, London, ON N6A 5C1, Canada
基金
加拿大健康研究院;
关键词
Iron; Siderophore; Staphylococcus; Iron acquisition; ABC transporters; COAGULASE-NEGATIVE STAPHYLOCOCCI; COORDINATION CHEMISTRY; BINDING-PROTEIN; HYDROXAMATE TRANSPORT; ESCHERICHIA-COLI; MOLECULAR CHARACTERIZATION; REGULATED PROTEIN; STAPHYLOFERRIN-A; PLASMID COLV-K30; ABC TRANSPORTER;
D O I
10.1016/j.jinorgbio.2009.09.011
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Iron is frequently a growth-limiting nutrient due to its propensity to interact with oxygen to form insoluble precipitates and, therefore, biological systems have evolved specialized uptake mechanisms to obtain this essential nutrient. Many pathogenic bacteria are capable of obtaining stringently sequestered iron from animal hosts by one or both of the following mechanisms: extraction of heme from host erythrocyte and serum hemoproteins, or through the use of high affinity, iron-scavenging molecules termed siderophores. This review summarizes our current knowledge of siderophore-mediated iron acquisition systems in the genus Staphylococcus. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:282 / 288
页数:7
相关论文
共 85 条
[31]  
HAAG H, 1994, FEMS MICROBIOL LETT, V115, P125
[32]   Iron and metal regulation in bacteria [J].
Hantke, K .
CURRENT OPINION IN MICROBIOLOGY, 2001, 4 (02) :172-177
[33]   COORDINATION CHEMISTRY OF MICROBIAL IRON TRANSPORT COMPOUNDS .16. ISOLATION, CHARACTERIZATION, AND FORMATION-CONSTANTS OF FERRIC AEROBACTIN [J].
HARRIS, WR ;
CARRANO, CJ ;
RAYMOND, KN .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (10) :2722-2727
[34]   Identification and characterization of SirA, an iron-regulated protein from Staphylococcus aureus [J].
Heinrichs, JH ;
Gatlin, LE ;
Kunsch, C ;
Choi, GH ;
Hanson, MS .
JOURNAL OF BACTERIOLOGY, 1999, 181 (05) :1436-1443
[35]  
Huebner J, 1999, ANNU REV MED, V50, P223, DOI 10.1146/annurev.med.50.1.223
[36]   COORDINATION ISOMERS OF BIOLOGICAL IRON TRANSPORT COMPOUNDS .5. PREPARATION AND CHIRALITY OF CHROMIUM(III) ENTEROBACTIN COMPLEX AND MODEL TRIS(CATECHOL)CHROMIUM(III) ANALOGS [J].
ISIED, SS ;
KUO, G ;
RAYMOND, KN .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (07) :1763-1767
[37]   Surveillance and epidemiology of MRSA bacteraemia in the UK [J].
Johnson, AP ;
Pearson, A ;
Duckworth, G .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (03) :455-462
[38]   Living without Fur:: the subtlety and complexity of iron-responsive gene regulation in the symbiotic bacterium Rhizobium and other α-proteobacteria [J].
Johnston, Andrew W. B. ;
Todd, Jonathan D. ;
Curson, Andrew R. ;
Lei, Sun ;
Nikolaidou-Katsaridou, Nefeli ;
Gelfand, Mikhail S. ;
Rodionov, Dmitry A. .
BIOMETALS, 2007, 20 (3-4) :501-511
[39]   SIDEROPHORE BIOSYNTHESIS: A SUBSTRATE SPECIFICITY ASSAY FOR NONRIBOSOMAL PEPTIDE SYNTHETASE-INDEPENDENT SIDEROPHORE SYNTHETASES INVOLVING TRAPPING OF ACYL-ADENYLATE INTERMEDIATES WITH HYDROXYLAMINE [J].
Kadi, Nadia ;
Challis, Gregory L. .
COMPLEX ENZYMES IN MICROBIAL NATURAL PRODUCT BIOSYNTHESIS, PART A: OVERVIEW ARTICLES AND PEPTIDES, 2009, 458 :431-457
[40]   Identification and characterization of iron-regulated Bordetella pertussis alcaligin siderophore biosynthesis genes [J].
Kang, HY ;
Brickman, TJ ;
Beaumont, FC ;
Armstrong, SK .
JOURNAL OF BACTERIOLOGY, 1996, 178 (16) :4877-4884