Siderophore-mediated iron acquisition in the staphylococci

被引：60

作者：

Beasley, Federico C. ^{[1
]}

Heinrichs, David E. ^{[1
]}

机构：

[1] Univ Western Ontario, Dept Microbiol & Immunol, London, ON N6A 5C1, Canada

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 2010年 / 104卷 / 03期

基金：

加拿大健康研究院;

关键词：

Iron; Siderophore; Staphylococcus; Iron acquisition; ABC transporters; COAGULASE-NEGATIVE STAPHYLOCOCCI; COORDINATION CHEMISTRY; BINDING-PROTEIN; HYDROXAMATE TRANSPORT; ESCHERICHIA-COLI; MOLECULAR CHARACTERIZATION; REGULATED PROTEIN; STAPHYLOFERRIN-A; PLASMID COLV-K30; ABC TRANSPORTER;

D O I：

10.1016/j.jinorgbio.2009.09.011

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Iron is frequently a growth-limiting nutrient due to its propensity to interact with oxygen to form insoluble precipitates and, therefore, biological systems have evolved specialized uptake mechanisms to obtain this essential nutrient. Many pathogenic bacteria are capable of obtaining stringently sequestered iron from animal hosts by one or both of the following mechanisms: extraction of heme from host erythrocyte and serum hemoproteins, or through the use of high affinity, iron-scavenging molecules termed siderophores. This review summarizes our current knowledge of siderophore-mediated iron acquisition systems in the genus Staphylococcus. (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：282 / 288

页数：7

共 85 条

[1] Petrobactin-mediated iron transport in pathogenic bacteria: Coordination chemistry of an unusual 3,4-catecholate/citrate siderophore [J].

Abergel, Rebecca J. ;

Zawadzka, Anna M. ;

Raymond, Kenneth N. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (07) :2124-+

[2] Characterization of staphyloferrin A biosynthetic and transport mutants in staphylococcus aureus [J].

Beasley, Federico C. ;

Vines, Enrique D. ;

Grigg, Jason C. ;

Zheng, Qin ;

Liu, Suya ;

Lajoie, Gilles A. ;

Murphy, Michael E. P. ;

Heinrichs, David E. .

MOLECULAR MICROBIOLOGY, 2009, 72 (04) :947-963

[3] Management of common bacterial infections of the skin [J].

Bernard, Philippe .

CURRENT OPINION IN INFECTIOUS DISEASES, 2008, 21 (02) :122-128

[4] Ralstonia solanacearum iron scavenging by the siderophore staphyloferrin B is controlled by PhcA, the global virulence regulator [J].

Bhatt, G ;

Denny, TP .

JOURNAL OF BACTERIOLOGY, 2004, 186 (23) :7896-7904

[5] In vitro functional characterization of BtuCD-F, the Escherichia coli ABC transporter for vitamin B12 uptake [J].

Borths, EL ;

Poolman, B ;

Hvorup, RN ;

Locher, KP ;

Rees, DC .

BIOCHEMISTRY, 2005, 44 (49) :16301-16309

[6] Iron(III) coordination properties of a pyoverdin siderophore produced by Pseudomonas putida ATCC 33015 [J].

Boukhalfa, Hakim ;

Reilly, Sean D. ;

Michalczyk, Ryszard ;

Iyer, Srinivas ;

Neu, Mary P. .

INORGANIC CHEMISTRY, 2006, 45 (14) :5607-5616

[7] NUCLEOTIDE-SEQUENCE OF THE FHUC AND FHUD GENES INVOLVED IN IRON(III) HYDROXAMATE TRANSPORT - DOMAINS IN FHUC HOMOLOGOUS TO ATP-BINDING PROTEINS [J].

BURKHARDT, R ;

BRAUN, V .

MOLECULAR & GENERAL GENETICS, 1987, 209 (01) :49-55

[8] Molecular characterization of the iron-hydroxamate uptake system in Staphylococcus aureus [J].

Cabrera, G ;

Xiong, AM ;

Uebel, M ;

Singh, VK ;

Jayaswal, RK .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2001, 67 (02) :1001-1003

[9] Coordination chemistry of the carboxylate type siderophore rhizoferrin: The iron(III) complex and its metal analogs [J].

Carrano, CJ ;

Drechsel, H ;

Kaiser, D ;

Jung, G ;

Matzanke, B ;

Winkelmann, G ;

Rochel, N ;

AlbrechtGary, AM .

INORGANIC CHEMISTRY, 1996, 35 (22) :6429-6436

[10] A widely distributed bacterial pathway for siderophore biosynthesis independent of nonribosomal peptide synthetases [J].

Challis, GL .

CHEMBIOCHEM, 2005, 6 (04) :601-611

← 1 2 3 4 5 6 7 8 9 →