Caveat medicus! Pulmonary hypertension in the elderly: a word of caution

被引:36
作者
Boilson, Barry A. [1 ]
Schirger, John A. [1 ]
Borlaug, Barry A. [1 ]
机构
[1] Mayo Clin Rochester, Dept Med, Div Cardiovasc Dis, Rochester, MN 55905 USA
关键词
Heart failure with preserved ejection fraction; Pulmonary hypertension; Diagnosis; INHALED NITRIC-OXIDE; SYSTOLIC HEART-FAILURE; CARDIOMYOPATHY; PRESSURE;
D O I
10.1093/eurjhf/hfp171
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure with preserved ejection fraction (HFpEF) is a common but under-recognized cause of pulmonary hypertension (PH), particularly among the elderly. While elevated pulmonary artery pressures are clearly associated with increased mortality in HFpEF, it remains unknown whether or how pulmonary vascular disease in HFpEF should be treated. This case emphasizes the importance of maintaining a high index of suspicion for HFpEF in elderly patients presenting with PH and illustrates potential hazards associated with selective pulmonary vasodilation in this growing population.
引用
收藏
页码:89 / 93
页数:5
相关论文
共 15 条
  • [1] Diagnosis and Assessment of Pulmonary Arterial Hypertension
    Badesch, David B.
    Champion, Hunter C.
    Gomez Sanchez, Miguel Angel
    Hoeper, Marius M.
    Loyd, James E.
    Manes, Alessandra
    McGoon, Michael
    Naeije, Robert
    Olschewski, Horst
    Oudiz, Ronald J.
    Torbicki, Adam
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (01) : S55 - S66
  • [2] Left ventricular diastolic filling in the elderly: The Cardiovascular Health Study
    Gardin, JM
    Arnold, AM
    Bild, DE
    Smith, VE
    Lima, JAC
    Klopfenstein, HS
    Kitzman, DW
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1998, 82 (03) : 345 - 351
  • [3] Left ventricular chamber function during inhaled nitric oxide in patients with dilated cardiomyopathy
    Hayward, CS
    Kalnins, WV
    Rogers, P
    Feneley, MP
    Macdonald, PS
    Kelly, RP
    [J]. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1999, 34 (05) : 749 - 754
  • [4] Kageji Y, 1996, J Card Fail, V2, P215, DOI 10.1016/S1071-9164(96)80044-3
  • [5] Age-Associated Increases in Pulmonary Artery Systolic Pressure in the General Population
    Lam, Carolyn S. P.
    Borlaug, Barry A.
    Kane, Garvan C.
    Enders, Felicity T.
    Rodeheffer, Richard J.
    Redfield, Margaret M.
    [J]. CIRCULATION, 2009, 119 (20) : 2663 - 2670
  • [6] Sildenafil improves exercise capacity and quality of life in patients with systolic heart failure and secondary pulmonary hypertension
    Lewis, Gregory D.
    Shah, Ravi
    Shahzad, Khurram
    Camuso, Janice M.
    Pappagianopoulos, Paul P.
    Hung, Judy
    Tawakol, Ahmed
    Gerszten, Robert E.
    Systrom, David M.
    Bloch, Kenneth D.
    Semigran, Marc J.
    [J]. CIRCULATION, 2007, 116 (14) : 1555 - 1562
  • [7] Sildenafil improves exercise hemodynamics and oxygen uptake in patients with systolic heart failure
    Lewis, Gregory D.
    Lachmann, Justine
    Camuso, Janice
    Lepore, John J.
    Shin, Jordan
    Martinovic, Maryann E.
    Systrom, David M.
    Bloch, Kenneth D.
    Semigran, Marc J.
    [J]. CIRCULATION, 2007, 115 (01) : 59 - 66
  • [8] CARDIOVASCULAR EFFECTS OF INHALED NITRIC-OXIDE IN PATIENTS WITH LEFT-VENTRICULAR DYSFUNCTION
    LOH, E
    STAMLER, JS
    HARE, JM
    LOSCALZO, J
    COLUCCI, WS
    [J]. CIRCULATION, 1994, 90 (06) : 2780 - 2785
  • [9] Cardiovascular effects of inhaled nitric oxide in a canine model of cardiomyopathy
    Loh, E
    Lankford, EB
    Polidori, DJ
    Doering-Lubit, EB
    Hanson, CW
    Acker, MA
    [J]. ANNALS OF THORACIC SURGERY, 1999, 67 (05) : 1380 - 1385
  • [10] Secondary pulmonary hypertension in chronic heart failure - The role of the endothelium in pathophysiology and management
    Moraes, DL
    Colucci, WS
    Givertz, MM
    [J]. CIRCULATION, 2000, 102 (14) : 1718 - 1723