During Transitions Proteins Make Fleeting Bonds

被引：10

作者：

Boehr, David D. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

CELL | 2009年 / 139卷 / 06期

关键词：

SIGNALING PROTEIN; DYNAMICS;

D O I：

10.1016/j.cell.2009.11.031

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

How do proteins efficiently and precisely shift from one conformation to another? Gardino et al. (2009) show that transient hydrogen bonds are critical to the conformational transition of the nitrogen regulatory protein NtrC between its native state and its active state.

引用

页码：1049 / 1051

页数：4

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