Coextensive synchronized SLO-OCT with adaptive optics for human retinal imaging

被引：22

作者：

Azimipour, Mehdi ^{[1
]}

Jonnal, Ravi S. ^{[1
]}

Werner, John S. ^{[1
]}

Zawadzki, Robert J. ^{[1
,2
]}

机构：

[1] UC Davis Eye Ctr, Dept Ophthalmol & Vis Sci, Vis Sci & Adv Retinal Imaging Lab VSRI, Sacramento, CA 95817 USA

[2] Univ Calif Davis, Dept Cell Biol & Human Anat, EyePod Small Anim Ocular Imaging Lab, Davis, CA 95616 USA

来源：

OPTICS LETTERS | 2019年 / 44卷 / 17期

关键词：

COHERENCE TOMOGRAPHY; HIGH-RESOLUTION; SYSTEM;

D O I：

10.1364/OL.44.004219

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We describe the details of a multimodal retinal imaging system which combines adaptive optics (AO) with an integrated scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT) imaging system. The OCT subsystem consisted of a swept-source, Fourier-domain mode-locked (FDML) laser, with a very high A-scan rate (1.6 MHz), whose beam was raster scanned on the retina by two scanners-one resonant scanner and one galvanometer. The high sweep rate of the FDML permitted the SLO and OCT to utilize the same scanners for in vivo retinal imaging and, unlike existing multimodal systems, concurrently acquired SLO frames and OCT volumes with approximate en face correspondence at a rate of 6 Hz. The AO provided diffraction-limited cellular resolution for both imaging channels. (C) 2019 Optical Society of America

引用

页码：4219 / 4222

页数：4

共 34 条

[1]

ANSI, 2014, AM NAT STAND SAF US, V7136

[2] Functional retinal imaging using adaptive optics swept-source OCT at 1.6 MHz [J].

Azimipour, Mehdi ;

Migacz, Justin, V ;

Zawadzki, Robert J. ;

Werner, John S. ;

Jonnal, Ravi S. .

OPTICA, 2019, 6 (03) :300-303

[3] Intraframe motion correction for raster-scanned adaptive optics images using strip- based cross-correlation lag biases [J].

Azimipour, Mehdi ;

Zawadzki, Robert J. ;

Gorczynska, Iwona ;

Migacz, Justin ;

Werner, John S. ;

Jonnal, Ravi S. .

PLOS ONE, 2018, 13 (10)

[4] Transverse chromatic offsets with pupil displacements in the human eye: sources of variability and methods for real-time correction [J].

Boehm, Alexandra E. ;

Privitera, Claudio M. ;

Schmidt, Brian P. ;

Roorda, Austin .

BIOMEDICAL OPTICS EXPRESS, 2019, 10 (04) :1691-1706

[5] Imaging of Vascular Wall Fine Structure in the Human Retina Using Adaptive Optics Scanning Laser Ophthalmoscopy [J].

Chui, Toco Y. P. ;

Gast, Thomas J. ;

Burns, Stephen A. .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2013, 54 (10) :7115-7124

[6] Noninvasive imaging of the human rod photoreceptor mosaic using a confocal adaptive optics scanning ophthalmoscope [J].

Dubra, Alfredo ;

Sulai, Yusufu ;

Norris, Jennifer L. ;

Cooper, Robert F. ;

Dubis, Adam M. ;

Williams, David R. ;

Carroll, Joseph .

BIOMEDICAL OPTICS EXPRESS, 2011, 2 (07) :1864-1876

[7]

ENOCH JM, 1961, AM J OPHTHALMOL, V51, P1107

[8] Adaptive optics SLO/OCT for 3D imaging of human photoreceptors in vivo [J].

Felberer, Franz ;

Kroisamer, Julia-Sophie ;

Baumann, Bernhard ;

Zotter, Stefan ;

Schmidt-Erfurth, Ursula ;

Hitzenberger, Christoph K. ;

Pircher, Michael .

BIOMEDICAL OPTICS EXPRESS, 2014, 5 (02) :439-456

[9] Multimodal adaptive optics retinal imager: design and performance [J].

Hammer, Daniel X. ;

Ferguson, R. Daniel ;

Mujat, Mircea ;

Patel, Ankit ;

Plumb, Emily ;

Iftimia, Nicusor ;

Chui, Toco Y. P. ;

Akula, James D. ;

Fulton, Anne B. .

JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2012, 29 (12) :2598-2607

[10] OPTICAL COHERENCE TOMOGRAPHY [J].

HUANG, D ;

SWANSON, EA ;

LIN, CP ;

SCHUMAN, JS ;

STINSON, WG ;

CHANG, W ;

HEE, MR ;

FLOTTE, T ;

GREGORY, K ;

PULIAFITO, CA ;

FUJIMOTO, JG .

SCIENCE, 1991, 254 (5035) :1178-1181

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