Bidirectional isotachophoresis on a planar chip with integrated conductivity detection

被引：45
|
作者：
Prest, JE [1 ]
Baldock, SJ [1 ]
Fielden, PR [1 ]
Goddard, NJ [1 ]
Brown, BJT [1 ]
机构：
[1] UMIST, Dept Instrumentat & Analyt Sci, Manchester M60 1QD, Lancs, England
来源：
ANALYST | 2002年 / 127卷 / 11期
关键词：
D O I：
10.1039/b207462a
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The use of a miniaturised planar separation device with integrated conductivity detection for performing bidirectional isotachophoresis (ITP) is described. The chips were produced in poly( methyl methacrylate) (PMMA) using a milling procedure. To enable bidirectional ITP the devices were designed to inject samples into the centre of the separation channel and incorporated two integrated on-column conductivity detectors, positioned at opposite ends of this channel. When used with a hydrodynamic sample transport system the devices were used for the analysis of a range of small ions: NH4+; Na+; Mg2+; Ca2+; Li+; NO3-; ClO4-; SO41; F-. Results successfully achieved included the simultaneous separation of three anions and three cations.
引用
收藏
页码：1413 / 1419
页数：7
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