Extragenital adenosarcoma: A case report, review of the literature, and management discussion

被引:20
|
作者
Huang, Gloria S. [1 ]
Arend, Rebecca C.
Sakaris, Antoinette
Hebert, Tiffany M.
Goldberg, Gary L.
机构
[1] Albert Einstein Coll Med, Dept Pathol, Dept Obstet & Gynecol & Womens Hlth, Div Gynecol Oncol, Bronx, NY 10461 USA
基金
美国国家卫生研究院;
关键词
Adenosarcoma; Endometriosis; Sarcoma; Chemotherapy; GEMCITABINE PLUS DOCETAXEL; MULLERIAN ADENOSARCOMA; SARCOMATOUS OVERGROWTH; CLINICOPATHOLOGICAL ANALYSIS; ENDOMETRIOSIS; UTERUS;
D O I
10.1016/j.ygyno.2009.07.033
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background. Mullerian adenosarcoma is a rare mixed epithelial-mesenchymal tumor. An extragenital site of origin and sarcomatous overgrowth are associated with aggressive clinical behavior. Case. We present a rare case of extragenital adenosarcoma with sarcomatous overgrowth and coexistent endometriosis. She was treated with initial cytoreductive surgery and chemotherapy. She underwent a second surgery for management of a high-grade bowel obstruction, due to pathologically confirmed recurrent intraperitoneal adenosarcoma. A complete clinical response was achieved with liposomal doxorubicin, and the patient remains disease-free eighteen months after completion of chemotherapy. Conclusion. Liposomal doxorubicin appears to be an active agent for the treatment of adenosarcoma with sarcomatous overgrowth. In addition, we conclude front our review of all reported cases of extragenital adenosarcoma that concurrent endometriosis may represent a favorable prognostic factor. (C) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:472 / 475
页数:4
相关论文
共 50 条
  • [21] Extragenital malignant mixed mesodermal tumor: case report and review of the literature
    Ergeneli, MH
    Demirhan, B
    Duran, EH
    Erdogan, M
    EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, 1997, 18 (06) : 531 - 533
  • [22] PRIMARY EXTRAGENITAL CHORIOCARCINOMA IN MALE SUBJECT - CASE REPORT AND REVIEW OF LITERATURE
    FINE, G
    SMITH, RW
    PACHTER, MR
    AMERICAN JOURNAL OF MEDICINE, 1962, 32 (05): : 776 - +
  • [23] Mullerian adenosarcoma: An uncommon case and review of the literature
    Montezuma, D.
    Loureiro, J.
    VIRCHOWS ARCHIV, 2016, 469 : S283 - S283
  • [24] Mullerian adenosarcoma of vagina arising in persistent endometriosis: report of a case and review of the literature
    Liu, LT
    Davidson, S
    Singh, M
    GYNECOLOGIC ONCOLOGY, 2003, 90 (02) : 486 - 490
  • [25] Uterine preservation in a young patient with adenosarcoma of the uterus - Case report and review of literature
    Goh, C.
    Lin, X. H.
    Chin, P. S.
    Lim, Y. K.
    GYNECOLOGIC ONCOLOGY REPORTS, 2018, 25 : 27 - 29
  • [26] Coexistence of uterine adenosarcoma and endometrioid endometrial carcinoma: A case report and literature review
    Wang, Wenyan
    Li, Jianyu
    Xu, Juan
    Tang, Hao
    Chen, Ying
    Guo, Deyu
    SCIENCE PROGRESS, 2024, 107 (04)
  • [27] Mullerian adenosarcoma (heterologous) of the cervix with sarcomatous overgrowth: a case report with review of literature
    Duggal, Rajan
    Nijhawan, Raje
    Aggarwal, Neelam
    Sikka, Pooja
    JOURNAL OF GYNECOLOGIC ONCOLOGY, 2010, 21 (02) : 125 - 128
  • [28] EXTRAGENITAL MALIGNANT MIXED MULLERIAN TUMOR - CASE-REPORT AND REVIEW OF THE LITERATURE
    HASIUK, AS
    PETERSEN, RO
    HANJANI, P
    GRIFFIN, TD
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1984, 81 (01) : 102 - 105
  • [29] A case report and a review of the literature of the most common extragenital localization of primary syphilis
    Rampi, Andrea
    Dane, Giulia
    Lissoni, Alessandra
    Vinciguerra, Alessandro
    Indelicato, Pietro
    Abati, Silvio
    B-ENT, 2021, 17 (01): : 37 - 41
  • [30] Extragenital Bullous Lichen Sclerosus in a Pediatric Patient: A Case Report and Literature Review
    Shiver, Mallory
    Papasakelariou, Catherine
    Brown, Jameel Ahmad
    Wirges, Marla
    Kincannon, Jay
    PEDIATRIC DERMATOLOGY, 2014, 31 (03) : 383 - 385