Asymmetric base pairing in the complex 5-fluorocytosinium chloride/5-fluorocytosine monohydrate

被引：30
作者：
Portalone, Gustavo [1 ]
Colapietro, Marcello [1 ]
机构：
[1] Univ Rome 1 La Sapienza, Dept Chem, I-00185 Rome, Italy
来源：
JOURNAL OF CHEMICAL CRYSTALLOGRAPHY | 2007年 / 37卷 / 02期
关键词：
5-fluorocytosine; 5-fluorocytosinium chloride; nucleobases; crystal engineering; molecular recognition;
D O I：
10.1007/s10870-006-9169-2
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The structure of the complex 5-Fluorocytosinium chloride/5-Fluorocytosine monohydrate has been studied by X-ray diffraction methods. It crystallizes in the monoclinic system, space group P 2(1)/ n, a = 7.1257 ( 15), b = 8.351 ( 3), c = 21.520 ( 4) angstrom, beta = 92.89 ( 8)degrees, V = 1279.0 ( 6) angstrom(3), Z = 4. The structure consists of triple hydrogen-bonded 5-Fluorocytosine pairs, water molecules and chloride anions. Asymmetric reversed Watson-Crick base pairing occurs between one protonated (5FcytH(+)) and one neutral 5-Fluorocytosine (5Fcyt) molecule.
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页码：141 / 145
页数：5
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