Biosynthesis of polyketides by trans-AT polyketide synthases

被引：261

作者：

Helfrich, Eric J. N. ^{[1
]}

Piel, Joern ^{[1
]}

机构：

[1] ETH, Inst Microbiol, Vladimir Prelog Weg 1-5-10, CH-8093 Zurich, Switzerland

来源：

NATURAL PRODUCT REPORTS | 2016年 / 33卷 / 02期

基金：

瑞士国家科学基金会;

关键词：

GRAM-NEGATIVE BACTERIA; ELONGATION-FACTOR-TU; SPONGE THEONELLA-SWINHOEI; ANTITUMOR ANTIBIOTIC LEINAMYCIN; NUDIBRANCH HEXABRANCHUS-SANGUINEUS; BACILLUS-AMYLOLIQUEFACIENS FZB42; MACROCYCLIC LACTONE ANTIBIOTICS; LANKACIDIN-GROUP ANTIBIOTICS; FUNGUS RHIZOPUS-MICROSPORUS; GLUCONOBACTER SP W-315;

D O I：

10.1039/c5np00125k

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Covering 2000 to June 2015 This review discusses the biosynthesis of natural products that are generated by trans-AT polyketide synthases, a family of catalytically versatile enzymes that represents one of the major group of proteins involved in the production of bioactive polyketides. The article includes 609 references and covers the literature from 2009 through June 2015.

引用

页码：231 / 316

页数：86

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