Constituents of aromatic plants: elemicin

被引：28

作者：

De Vincenzi, M

De Vincenzi, A

Silano, M

机构：

[1] Ist Super Sanita, Dept Metab & Pathol Biochem, I-161 Rome, Italy

[2] Univ Roma La Sapienza, Residency Sport Med, Rome, Italy

来源：

FITOTERAPIA | 2004年 / 75卷 / 06期

关键词：

Petroselinum sativum; Miristica fragrans; Canarium commune; elemicin;

D O I：

10.1016/j.fitote.2004.05.003

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

No results of short-term or chronic toxicity studies have been found. Elemicin did induce UDS in hepatocytes from male rats. Studies on carcinogenicity were negative, but the 1'-hydroxy-metabolite of elemicin gave positive and negative results. The total intake of elemicin from essential oil seems to be limited. The main source of intake appears to be nutmeg. Further studies are needed to evaluate if the intake of elemicin may represent a health risk. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：615 / 618

页数：4

共 8 条

[1]

EEVERTSBUSCH V, 1956, ARCH INT PHARMACOD T, P105

[2]

FENAROLI G, 1995, HDB FLAVOUR INGREDIE

[3] GENOTOXICITY OF THE ALKENYLBENZENES ALPHA-ASARONE AND BETA-ASARONE, MYRISTICIN AND ELEMICIN AS DETERMINED BY THE UDS ASSAY IN CULTURED RAT HEPATOCYTES [J].