Digital microfluidics for cell manipulation

被引：35

作者：

Pang, Long ^{[1
,2
]}

Ding, Jing ^{[2
]}

Liu, Xi-Xian ^{[2
]}

Fan, Shih-Kang ^{[3
]}

机构：

[1] Xian Med Univ, Shaanxi Key Lab Brain Disorders, Sch Basic Med Sci, Xian 710021, Shaanxi, Peoples R China

[2] Xi An Jiao Tong Univ, Sch Energy & Power Engn, Key Lab Thermofluid Sci & Engn MOE, Xian 710049, Shaanxi, Peoples R China

[3] Natl Taiwan Univ, Dept Mech Engn, Taipei 10617, Taiwan

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2019年 / 117卷

关键词：

ELECTROWETTING-BASED ACTUATION; LIQUID DROPLETS; CHIP; SEPARATION; DIELECTROPHORESIS; HETEROGENEITY; TECHNOLOGY; RESISTANCE; PLATFORM; CULTURE;

D O I：

10.1016/j.trac.2019.06.008

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A droplet-based technique to handle liquids called digital microfluidics (DMF) has attracted attention for cell manipulation (e.g., cell culture, cell sorting and single-cell analysis). With DMF, one manipulates droplets, of size ranging from picolitre to microlitre, on a planar surface by means of an electric field. DMF hence becomes an appealing platform to use for eventual integration into standard biological workflows. In this paper our aim is to provide a synopsis of cutting-edge developments in DMF-based cell manipulation, and to focus particularly on cell culture, cell sorting and single-cell applications. (C) 2019 Elsevier B.V. All rights reserved.

引用

页码：291 / 299

页数：9

共 50 条

[21] Virtual microfluidics for digital quantification and single-cell sequencing
Xu, Liyi
Brito, Ilana L.
Alm, Eric J.
Blainey, Paul C.
NATURE METHODS, 2016, 13 (09) : 759 - 762
[22] Particle Manipulation Methods in Droplet Microfluidics
Tenje, Maria
Fornell, Anna
Ohlin, Mathias
Nilsson, Johan
ANALYTICAL CHEMISTRY, 2018, 90 (03) : 1434 - 1443
[23] Digital Microfluidics for Automated Hanging Drop Cell Spheroid Culture
Aijian, Andrew P.
Garrell, Robin L.
JALA, 2015, 20 (03): : 283 - 295
[24] Virtual microfluidics for digital quantification and single-cell sequencing
Xu L.
Brito I.L.
Alm E.J.
Blainey P.C.
Nature Methods, 2016, 13 (9) : 759 - 762
[25] Microfluidics As a Tool for Micro-Manipulation
Potgieter, S.
Land, K.
Sparrow, R.
PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF THE WORLD ASSOCIATION OF LASER THERAPY, 2008, : 151 - 155
[26] Digital Microfluidics for Immunoprecipitation
Seale, Brendon
Lam, Charis
Rackus, Darius G.
Chamberlain, M. Dean
Liu, Chang
Wheeler, Aaron R.
ANALYTICAL CHEMISTRY, 2016, 88 (20) : 10223 - 10230
[27] Digital microfluidics with impedance sensing for integrated cell culture and analysis
Shih, Steve C. C.
Barbulovic-Nad, Irena
Yang, Xuning
Fobel, Ryan
Wheeler, Aaron R.
BIOSENSORS & BIOELECTRONICS, 2013, 42 : 314 - 320
[28] Perspectives on digital microfluidics
Freire, Sergio L. S.
SENSORS AND ACTUATORS A-PHYSICAL, 2016, 250 : 15 - 28
[29] Digital Manufacturing for Microfluidics
Naderi, Arman
Bhattacharjee, Nirveek
Folch, Albert
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 21, 2019, 21 : 325 - 364
[30] Digital microfluidics on a wire
Gilet, T.
Terwagne, D.
Vandewalle, N.
APPLIED PHYSICS LETTERS, 2009, 95 (01)

← 1 2 3 4 5 →