Microbiological and epidemiological evaluation of carbapenem-resistant Acinetobacter baumannii clones isolated at an intensive care unit of a University Hospital in Buenos Aires city

Microbiological and epidemiological evaluation of carbapenem-resistant Acinetobacter baumannii clones isolated at an intensive care unit of a University Hospital in Buenos Aires city. From June to December 2004, thirty-three carbapenem-resistant Acinetobacter baumannii isolates recovered from twenty nine patients at the intensive care unit in Hospital de Clinicas, Universidad de Buenos Aires, were studied. The isolates were categorized by molecular methods as: clone I (n = 14), clon IV (n = 7), clone III (n = 6), clone VI (n = 3), clone II (n = 2) and clone X (n = 1). Twenty one isolates were recovered from lower respiratory tract samples, 11 of which belonged to clon I. Clone III isolates were mainly recovered from non-respiratory samples (5/6). Clone IV isolates were recovered from patients not receiving previous imipenem therapy. The majority of the isolates belonging to clones I and IV were able to survive on inert materials for more than 5 days, whereas adhesion to catheters was observed in isolates belonging to clones I and III, especially in those related to bacteremia. Clone III isolates showed colistin, gentamicin and levofloxacin susceptibility, whereas clone I isolates and most from clone IV were only susceptible to colistin and tetracyclines.