Araguspongines K and L, new bioactive bis-1-oxaquinolizidine N-oxide alkaloids from Red Sea specimens of Xestospongia exigua

被引：40

作者：

Orabi, KY ^{[1
]}

El Sayed, KA

Hamann, MT

Dunbar, DC

Al-Said, MS

Higa, T

Kelly, M

机构：

[1] King Saud Univ, Coll Pharm, Dept Pharmacognosy, Riyadh 11451, Saudi Arabia

[2] Univ Mississippi, Sch Pharm, Dept Pharmacognosy, University, MS 38677 USA

[3] Univ Ryukyus, Coll Sci, Dept Marine Chem, Okinawa 9030213, Japan

[4] NIWA Ltd, Auckland, New Zealand

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 12期

关键词：

D O I：

10.1021/np0202226

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

In addition to the previously reported (+)-araguspongine A, (+)-araguspongine C, (+)-araguspongine D, (-)-araguspongine E, and (+)-xestospongin 13, two new N-oxide araguspongines, (+)-araguspongine K and (+)-araguspongine L, are described here. Their structures were established on the basis of spectral analyses including H-1-N-15 HMBC. The promising in vitro antimalarial and antituberculosis activities of araguspongine C are reported.

引用

页码：1782 / 1785

页数：4

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