Successful treatment of life-threatening Panton-Valentine leucocidin positive Staphylococcus aureus pneumonia with antibiotics and immunoglobulins targeting the toxin production

被引：6
作者：
Libert, N. [1 ]
Borne, M. [1 ]
Janvier, F. [2 ]
Batjom, E. [1 ]
Cirodde, A. [1 ]
Nizou, J. -Y. [2 ]
Brinquin, L. [1 ]
机构：
[1] Hop Instruct Armees Val de Grace, Serv Anesthesie & Reanimat, F-75005 Paris, France
[2] Hop Instruct Armees Val de Grace, Serv Biol, F-75005 Paris, France
来源：
REVUE DE MEDECINE INTERNE | 2009年 / 30卷 / 10期
关键词：
Panton-Valentine leucocidin; Immunoglobulins; Antitoxin antibiotics; Pneumonia; Staphylococcus aureus; Influenza; NECROTIZING PNEUMONIA; LEUKOCIDIN; ASSOCIATION;
D O I：
10.1016/j.revmed.2008.11.014
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a patient who presented a severe Panton-Valentine-secreting methicillin-susceptible Staphylococcus aureus pneumonia with threatening multi-organ failure including acute respiratory distress syndrome, cardiac failure, renal failure and disseminated intravascular coagulation. Clinical and biological disease course using empiric therapy with treatment directed against toxin production (linezolid, clindamycin and intravenous immunoglobulins) was found to be quickly effective. (C) 2009 Societe nationale francaise de medecine interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：907 / 910
页数：4
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