DNA hypermethylation of IRX4 is a frequent event that may confer growth advantage to pancreatic cancer cells

被引：3
|
作者：
Chakma, Kanchan [1 ]
Gu, Zhaodi [2 ]
Motoi, Fuyuhiko [3 ]
Unno, Michiaki [3 ]
Horii, Akira [2 ]
Fukushige, Shinichi [2 ]
机构：
[1] Univ Chittagong, Dept Biochem & Mol Biol, Chittagong, Bangladesh
[2] Tohoku Univ, Dept Mol Pathol, Sch Med, Sendai, Miyagi, Japan
[3] Tohoku Univ, Dept Gastroenterol Surg, Sch Med, Sendai, Miyagi, Japan
来源：
CANCER RESEARCH | 2019年 / 79卷 / 13期
关键词：
D O I：
10.1158/1538-7445.AM2019-821
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
821
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells
    Zhang, Yanqun
    Ji, Shenying
    Zhang, Xiangyu
    Lu, Mengyun
    Hu, Yihong
    Han, Yucheng
    Shui, Guanghou
    Lam, Sin Man
    Zou, Xianqiong
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2022, 18 (13): : 4963 - 4983
  • [42] DNA methylation of HSD17B4 alters cell membrane homeostasis, which may enhance drug sensitivity in breast cancer cells
    Hattori, Naoko
    Arai, Nobuaki
    Yamashita, Satoshi
    Mukai, Hirofumi
    Ushijima, Toshikazu
    CANCER SCIENCE, 2023, 114 : 2112 - 2112
  • [43] RNA interference targeting against S100A4 suppresses cell growth and motility and induces apoptosis in human pancreatic cancer cells
    Tabata, Takahiro
    Tsukamoto, Nobukazu
    Fooladi, Abbas Ali Imani
    Yamanaka, Sumitaka
    Furukawa, Toru
    Ishida, Masaharu
    Sato, Daisuke
    Gu, Zhaodi
    Nagase, Hiroki
    Egawa, Shinichi
    Sunamura, Makoto
    Horii, Akira
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 390 (03) : 475 - 480
  • [44] Targeting TM4SF5 with anti-TM4SF5 monoclonal antibody suppresses the growth and motility of human pancreatic cancer cells
    Park, Sangkyu
    Kim, Dongbum
    Park, Jeong-A
    Kwon, Hyung-Joo
    Lee, Younghee
    ONCOLOGY LETTERS, 2020, 19 (01) : 641 - 650
  • [45] Characterization of human mucin gene MUC4 promoter -: Importance of growth factors and proinflammatory cytokines for its regulation in pancreatic cancer cells
    Perrais, M
    Pigny, P
    Ducourouble, MP
    Petitprez, D
    Porchet, N
    Aubert, JP
    Van Seuningen, I
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (33) : 30923 - 30933
  • [46] Cyclopamine increases the radiosensitivity of human pancreatic cancer cells by regulating the DNA repair signal pathway through an epidermal growth factor receptor-dependent pathway
    Wu, Xiao-Yang
    Che, Jun
    Sun, Ke-Kang
    Shen, Xiao-Jun
    Yang, Dong
    Zhong, Ning
    Zhao, Hua
    MOLECULAR MEDICINE REPORTS, 2013, 8 (04) : 979 - 983
  • [47] A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model
    Park, Sangkyu
    Kim, Dongbum
    Wu, Guang
    Jung, Harry
    Park, Jeong-A
    Kwon, Hyung-Joo
    Lee, Younghee
    ONCOTARGETS AND THERAPY, 2018, 11 : 8655 - 8672
  • [48] Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells
    Wei, Daoyan
    Kanai, Masahsi
    Jia, Zhiliang
    Le, Xiangdong
    Xie, Keping
    CANCER RESEARCH, 2008, 68 (12) : 4631 - 4639
  • [49] Inhibition of STAT3Tyr705 phosphorylation by Smad4 suppresses transforming growth factor β-mediated invasion and metastasis in pancreatic cancer cells
    Zhao, Shujie
    Venkatasubbarao, Kolaparthi
    Lazor, Jillian W.
    Sperry, Jane
    Jin, Changqing
    Cao, Lin
    Freeman, James W.
    CANCER RESEARCH, 2008, 68 (11) : 4221 - 4228
  • [50] Targeting cancer stem cells and vasculatures by a novel anti-d1I4 antibody inhibits pancreatic tumor growth and delays tumor recurrence
    Yen, Wan-Ching
    Fischer, Marcus
    Beviglia, Lucia
    Yeung, Pete
    Liu, Yuwang
    Kapoun, Ann
    Gurney, Austin
    Hoey, Timothy
    CANCER RESEARCH, 2009, 69
12345