Disseminated intravascular coagulation after Cerastes vipera envenomation in a 3-year-old child:: a case report

被引:18
作者
Lifshitz, M [1 ]
Kapelushnik, J
Ben-Harosh, M
Sofer, S
机构
[1] Soroka Univ, Med Ctr, Toxicol Unit, Beer Sheva, Israel
[2] Ben Gurion Univ Negev, Fac Hlth Sci, IL-84105 Beer Sheva, Israel
[3] Soroka Univ, Med Ctr, Hematol Unit, Beer Sheva, Israel
[4] Soroka Univ, Med Ctr, Pediat Intens Care Unit, Beer Sheva, Israel
关键词
Cerastes vipera; envenomation; children; coagulopathy;
D O I
10.1016/S0041-0101(99)00239-1
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
This study presents a case of severe disseminated intravascular coagulation (DIC) in a 3-year-old child following envenomation by the snake, Cerastes vipera. A literature search revealed very few similar cases. We describe a child who was bitten in his left foot by a snake identified as a C. vipera. Initial symptoms were relatively benign. Local signs included a hemorrhagic vesicle at the site of the bite with marked swelling of the entire leg. Twenty-four hours later, the child developed severe bleeding due to DIG, which lasted 5 days and required repeated administration of blood and blood products and total exchange transfusion. The patient was discharged from the hospital after 7 days in good condition. To the best of our knowledge, severe DIC following envenomation by a C. vipera has not been previously described in the literature. Treatment was essentially supportive. The case report indicates that a specific antivenin against this snake's venom should be made available in our area. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1593 / 1598
页数:6
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