Emerging trends in the treatment of rectal cancer

被引：14

作者：

Minsky, Bruce D. ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, 1400 Pressler St, Houston, TX 77030 USA

来源：

ACTA ONCOLOGICA | 2019年 / 58卷 / 10期

关键词：

SHORT-COURSE RADIOTHERAPY; TOTAL MESORECTAL EXCISION; COMPLETE CLINICAL-RESPONSE; QUALITY-OF-LIFE; PHASE-III TRIAL; TERM PREOPERATIVE RADIOTHERAPY; SHORT-COURSE RADIATION; NEOADJUVANT CHEMORADIOTHERAPY; ADJUVANT CHEMOTHERAPY; RANDOMIZED-TRIAL;

D O I：

10.1080/0284186X.2019.1629009

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The conventional treatment for cT3-T4 or node-positive clinically resectable rectal cancer is long course preoperative chemoradiation followed by surgery and postoperative adjuvant chemotherapy. Disadvantages of this approach include possible overtreatment of patients, 6 weeks of daily radiation treatment, and undetected metastatic disease. There are a number of emerging trends which are changing this approach to treatment. Selected topics included in this manuscript include the selective use of pelvic radiation, the role of radiation for a positive radial margin, the interval between radiation and surgery, non-operative management, new chemoradiation regimens, short vs. long course radiation, and the role of postoperative adjuvant chemotherapy.

引用

页码：1343 / 1351

页数：9

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