An analysis pipeline for the inference of protein-protein interaction networks

被引:3
作者
Taylor, Ronald C. [1 ]
Singhal, Mudita [1 ]
Daly, Don S.
Gilmore, Jason [2 ]
Cannon, William R.
Domico, Kelly [3 ]
White, Amanda M.
Auberry, Deanna L.
Auberry, Kenneth J.
Hooker, Brian S.
Hurst, Greg [4 ]
McDermott, Jason E.
McDonald, W. Hayes [5 ]
Pelletier, Dale A. [4 ]
Schmoyer, Denise [4 ]
Wiley, H. Steven
机构
[1] US DOE, Pacific NW Natl Lab, Computat Sci & Math Div, Computat Biol & Bioinformat Grp, Richland, WA 99352 USA
[2] Dartmouth Hitchcock Med Ctr, Lebanon, NH 03756 USA
[3] Battelle Seattle Res Ctr, Pacific NW Natl Lab, Seattle, WA 98109 USA
[4] Oak Ridge Natl Lab, Oak Ridge, TN 37831 USA
[5] Vanderbilt Univ, Sch Med, Mass Spectrometry Res Ctr, Nashville, TN 37232 USA
关键词
network inference pipeline; protein-protein interactions; networks; MS; mass spectrometry; Bayesian; REGULATORY NETWORKS; DATABASE; ANNOTATION; BIOVERSE;
D O I
10.1504/IJDMB.2009.029204
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We present a platform for the reconstruction of protein-protein interaction networks inferred from Mass Spectrometry (MS) bait-prey data. The Software Environment for Biological Network Inference (SEBINI), an environment for the deployment of network inference algorithms that use high-throughput data, forms the platform core. Among the many algorithms available in SEBINI is the Bayesian Estimator of Probabilities of Protein-Protein Associations (BEPro3) algorithm, which is used to infer interaction networks from such MS affinity isolation data. Also, the pipeline incorporates the Collective Analysis of Biological Interaction Networks (CABIN) software. We have thus created a structured workflow for protein-protein network inference and supplemental analysis.
引用
收藏
页码:409 / 430
页数:22
相关论文
共 32 条
  • [21] Bioverse: functional, structural and contextual annotation of proteins and proteomes
    McDermott, J
    Samudrala, R
    [J]. NUCLEIC ACIDS RESEARCH, 2003, 31 (13) : 3736 - 3737
  • [22] *MDEC BIOINF COR F, 2006, ARACNE ALG REC ACC C
  • [23] *OAK RIDG NAT LAB, 2007, MICR PROT PROT INT M
  • [24] Transcriptional regulatory networks in bacteria: from input signals to output responses
    Seshasayee, Aswin S. N.
    Bertone, Paul
    Fraser, Gillian M.
    Luscombe, Nicholas M.
    [J]. CURRENT OPINION IN MICROBIOLOGY, 2006, 9 (05) : 511 - 519
  • [25] Cytoscape: A software environment for integrated models of biomolecular interaction networks
    Shannon, P
    Markiel, A
    Ozier, O
    Baliga, NS
    Wang, JT
    Ramage, D
    Amin, N
    Schwikowski, B
    Ideker, T
    [J]. GENOME RESEARCH, 2003, 13 (11) : 2498 - 2504
  • [26] Statistically inferring protein-protein associations with affinity isolation LC-MS/MS assays
    Sharp, Julia L.
    Anderson, Kevin K.
    Hurst, Gregory B.
    Daly, Don S.
    Pelletier, Dale A.
    Cannon, William R.
    Auberry, Deanna L.
    Schmoyer, Denise D.
    McDonald, W. Hayes
    White, Amanda M.
    Hooker, Brian S.
    Victry, Kristin D.
    Buchanan, Michelle V.
    Kery, Vladimir
    Wiley, H. Steven
    [J]. JOURNAL OF PROTEOME RESEARCH, 2007, 6 (09) : 3788 - 3795
  • [27] CABIN: Collective Analysis of Biological Interaction Networks
    Singhal, Mudita
    Domico, Kelly
    [J]. COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2007, 31 (03) : 222 - 225
  • [28] DTASelect and contrast: Tools for assembling and comparing protein identifications from shotgun proteomics
    Tabb, DL
    McDonald, WH
    Yates, JR
    [J]. JOURNAL OF PROTEOME RESEARCH, 2002, 1 (01) : 21 - 26
  • [29] SEBINI: Software Environment for BIological Network Inference
    Taylor, Ronald C.
    Shah, Anuj
    Treatman, Charles
    Blevins, Meridith
    [J]. BIOINFORMATICS, 2006, 22 (21) : 2706 - 2708
  • [30] Wichadakul Duangdao, 2009, V541, P101, DOI 10.1007/978-1-59745-243-4_6