Synapsin Isoforms and Synaptic Vesicle Trafficking

被引：84

作者：

Song, Sang-Ho ^{[1
,2
]}

Augustine, George J. ^{[1
,2
]}

机构：

[1] Lee Kong Chian Sch Med, Singapore 637553, Singapore

[2] Inst Mol & Cell Biol, Singapore 138673, Singapore

来源：

MOLECULES AND CELLS | 2015年 / 38卷 / 11期

关键词：

neurotransmitter release; presynaptic terminals; synapsins; synaptic vesicles; vesicle trafficking; NEUROTRANSMITTER RELEASE; INHIBITORY SYNAPSES; TRANSMITTER RELEASE; PREFRONTAL CORTEX; BIPOLAR DISORDER; GENE-EXPRESSION; GIANT SYNAPSE; RESERVE POOL; DOMAIN E; SCHIZOPHRENIA;

D O I：

10.14348/molcells.2015.0233

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Synapsins were the first presynaptic proteins identified and have served as the flagship of the presynaptic protein field. Here we review recent studies demonstrating that different members of the synapsin family play different roles at presynaptic terminals employing different types of synaptic vesicles. The structural underpinnings for these functions are just beginning to be understood and should provide a focus for future efforts.

引用

页码：936 / 940

页数：5

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