Will the real Trypanosoma brucei rhodesiense please step forward?

被引：23
作者：
Gibson, W [1 ]
机构：
[1] Univ Bristol, Sch Biol Sci, Bristol BS8 1UG, Avon, England
来源：
TRENDS IN PARASITOLOGY | 2002年 / 18卷 / 11期
关键词：
D O I：
10.1016/S1471-4922(02)02390-5
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
The sleeping sickness trypanosomes Trypanosoma brucei rhodesiense and T. brucei gambiense are morphologically indistinguishable from each other and from T. brucei brucei, which does not infect humans. The relationships between these three subspecies have been controversial. Several years ago, the characterization of T. brucei gambiense was reviewed in an attempt to clarify and draw together the results, and to put them in the context of the biology of the organism. The discovery of a gene associated with human-serum resistance in T. brucei rhodesiense and the consequent reappraisal of the identity of this trypanosome prompt this companion article.
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收藏
页码：486 / 490
页数：5
相关论文
共 49 条
[1]  
[Anonymous], ANN TROPICAL MED PAR
[2]  
Ashcroft M. T., 1959, Tropical Diseases Bulletin, V56, P1073
[3]   A receptor-like flagellar pocket glycoprotein specific to Trypanosoma brucei gambiense [J].
Berberof, M ;
Pérez-Morga, D ;
Pays, E .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 113 (01) :127-138
[4]  
Biteau N, 2000, MOL BIOCHEM PARASIT, V105, P185, DOI 10.1016/S0166-6851(99)00171-1
[5]   QUANTITATION OF GENETIC-DIFFERENCES BETWEEN TRYPANOSOMA-BRUCEI GAMBIENSE, RHODESIENSE AND BRUCEI BY RESTRICTION ENZYME ANALYSIS OF KINETOPLAST DNA [J].
BORST, P ;
FASEFOWLER, F ;
GIBSON, WC .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1981, 3 (02) :117-131
[6]   IDENTIFICATION OF TRYPANOSOMA-BRUCEI-GAMBIENSE BY PCR AMPLIFICATION OF VARIANT SURFACE GLYCOPROTEIN GENES [J].
BROMIDGE, T ;
GIBSON, W ;
HUDSON, K ;
DUKES, P .
ACTA TROPICA, 1993, 53 (02) :107-119
[7]   THE SERUM RESISTANCE-ASSOCIATED (SRA) GENE OF TRYPANOSOMA-BRUCEI-RHODESIENSE ENCODES A VARIANT SURFACE GLYCOPROTEIN-LIKE PROTEIN [J].
DEGREEF, C ;
HAMERS, R .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1994, 68 (02) :277-284
[8]   A GENE EXPRESSED ONLY IN SERUM-RESISTANT VARIANTS OF TRYPANOSOMA-BRUCEI-RHODESIENSE [J].
DEGREEF, C ;
IMBERECHTS, H ;
MATTHYSSENS, G ;
VANMEIRVENNE, N ;
HAMERS, R .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 36 (02) :169-176
[9]  
DEGREEF C, 1992, ANN SOC BELG MED TR, V72, P13
[10]  
DUKE H. LYNDHURST, 1935, PARASITOLOGY, V27, P46, DOI 10.1017/S0031182000014943
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