Effects of a strong magnetic field on protein crystal growth

被引:78
作者
Wakayama, NI [1 ]
机构
[1] AIST, Tsukuba, Ibaraki 3058565, Japan
关键词
D O I
10.1021/cg025565g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The effect of a strong magnetic field on protein crystal growth is a new research field. Here, we review research on protein crystallization in magnetic fields, including magnetic orientation of protein crystals, magnetic control of effective gravity on earth, formation of protein crystals in various effective gravity, magnetic improvement in crystal quality, magnetic increase in viscosity of protein aqueous solutions, damping of natural convection by Lorentz force, etc. Four mechanisms are currently known to be involved in the effects of magnetic fields on protein crystal growth and all of them may contribute to the improvement of crystal quality. High quality protein crystals are critical in determining the structure of protein molecules by using X-ray diffraction analysis. Strong magnetic fields will help to improve crystal quality.
引用
收藏
页码:17 / 24
页数:8
相关论文
共 47 条
[1]   Protein crystals orientation in a magnetic field [J].
Astier, JP ;
Veesler, S ;
Boistelle, R .
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1998, 54 :703-706
[2]   α-amylase crystal growth investigated by in situ atomic force microscopy [J].
Astier, JP ;
Bokern, D ;
Lapena, L ;
Veesler, S .
JOURNAL OF CRYSTAL GROWTH, 2001, 226 (2-3) :294-302
[3]   Magnetic orientation as a tool to study the initial stage of crystallization of lysozyme [J].
Ataka, M ;
Katoh, E ;
Wakayama, NI .
JOURNAL OF CRYSTAL GROWTH, 1997, 173 (3-4) :592-596
[4]  
BEANGNON E, 1991, NATURE, V349, P470
[5]   MAGNETICALLY CONTROLLED CONVECTION IN A PARAMAGNETIC FLUID [J].
BRAITHWAITE, D ;
BEAUGNON, E ;
TOURNIER, R .
NATURE, 1991, 354 (6349) :134-136
[6]   PROTEIN CRYSTAL-GROWTH IN MICROGRAVITY [J].
DELUCAS, LJ ;
SMITH, CD ;
SMITH, HW ;
VIJAYKUMAR, S ;
SENADHI, SE ;
EALICK, SE ;
CARTER, DC ;
SNYDER, RS ;
WEBER, PC ;
SALEMME, FR ;
OHLENDORF, DH ;
EINSPAHR, HM ;
CLANCY, LL ;
NAVIA, MA ;
MCKEEVER, BM ;
NAGABHUSHAN, TL ;
NELSON, G ;
MCPHERSON, A ;
KOSZELAK, S ;
TAYLOR, G ;
STAMMERS, D ;
POWELL, K ;
DARBY, G ;
BUGG, CE .
SCIENCE, 1989, 246 (4930) :651-654
[7]   Apparent viscosity of human blood in a high static magnetic field [J].
Haik, Y ;
Pai, VN ;
Chen, CJ .
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2001, 225 (1-2) :180-186
[8]  
HIROSE R, 2002, P 6 S NEW MAGN SCI N, P60
[9]   Superconducting magnets for generating uniform magnetic force field [J].
Kiyoshi, T ;
Ozaki, O ;
Morita, H ;
Nakayama, H ;
Jin, HB ;
Wada, H ;
Wakayama, NI ;
Ataka, M .
IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, 1999, 9 (02) :362-365
[10]  
KIYOSHI T, Patent No. 6362712