Reimplantation of the resected tumour-bearing segment after recycling using liquid nitrogen for osteosarcoma

被引：32

作者：

Rahman, Mohamed Abdel ^{[1
]}

Bassiony, Ayman ^{[1
]}

Shalaby, Hisham ^{[1
]}

机构：

[1] Ain Shams Univ, Dept Orthopaed Surg, Demerdash Hosp, Cairo, Egypt

来源：

INTERNATIONAL ORTHOPAEDICS | 2009年 / 33卷 / 05期

关键词：

AUTOLOGOUS BONE-GRAFT; OF-THE-LITERATURE; LIMB-SALVAGE; CLINICAL-EXPERIENCE; RECONSTRUCTION; SURGERY; CRYOSURGERY; SARCOMA; CHEMOTHERAPY; CLASSIFICATION;

D O I：

10.1007/s00264-009-0773-6

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Reconstruction after en block resection of malignant tumours is still the subject of debate. We questioned the effectiveness of reconstruction by reimplanting the tumour-bearing segment after recycling in liquid nitrogen. Ten patients with osteosarcoma around the knee were included, with a mean age of 21 years. The operative technique included wide en bloc excision, debridement, and management of the resected segment with liquid nitrogen followed by reimplantation and internal fixation. At a mean follow-up of 4.5 years there was no local or systemic recurrence and the mean functional score was 82.4%. The frozen graft united proximally and distally in all but one patient in a period ranging from six to ten months. The effectiveness of this reconstruction technique in properly selected patients with osteosarcoma is comparable to other techniques of biological reconstruction with the added benefit of being simple, cheap and durable.

引用

页码：1365 / 1370

页数：6