Suicide genes: past, present and future perspectives

被引：59

作者：

Lal, S ^{[1
]}

Lauer, UM

Niethammer, D

Beck, JF

Schlegel, PG

机构：

[1] Univ Tubingen, Childrens Hosp, Dept Paediat Haematol & Oncol, D-72076 Tubingen, Germany

[2] Univ Tubingen, Dept Internal Med, D-72076 Tubingen, Germany

[3] Univ Greifswald, Childrens Hosp, D-17487 Greifswald, Germany

来源：

IMMUNOLOGY TODAY | 2000年 / 21卷 / 01期

关键词：

D O I：

10.1016/S0167-5699(99)01550-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Disappointing morbidity nd mortality rates in many disorders have necessitated the development of several 'biological' therapies. Once approach involves the use of suicide genes, Here, Shangara Lal and colleagues discuss the development of this branch of gene therapy in cell lines and animal models, and examine current studies, therapeutic applications and clinical trials.

引用

页码：48 / 54

页数：7

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