Alcohol use disorders

被引:492
作者
Carvalho, Andre F. [1 ,2 ]
Heilig, Markus [5 ]
Perez, Augusto [6 ]
Probst, Charlotte [1 ]
Rehm, Jurgen [1 ,2 ,3 ,4 ,7 ,8 ,9 ,10 ]
机构
[1] Ctr Addict & Mental Hlth, Inst Mental Hlth Policy Res, Toronto, ON M5S 2S1, Canada
[2] Univ Toronto, Dept Psychiat, Toronto, ON, Canada
[3] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
[4] Univ Toronto, Inst Med Sci, Toronto, ON, Canada
[5] Linkoping Univ, Dept Clin & Expt Med, Ctr Social & Affect Neurosci, Linkoping, Sweden
[6] Corp Nuevos Rumbos, Bogota, Colombia
[7] Ctr Addict & Mental Hlth, Campbell Family Mental Hlth Res Inst, Toronto, ON, Canada
[8] Tech Univ Dresden, Inst Clin Psychol & Psychotherapy, Dresden, Germany
[9] Tech Univ Dresden, Ctr Clin Epidemiol & Longitudinal Studies, Dresden, Germany
[10] Sechenov First Moscow State Med Univ, Inst Leadership & Hlth Management, Dept Int Hlth Projects, Moscow, Russia
基金
加拿大健康研究院; 瑞典研究理事会;
关键词
COGNITIVE BIAS MODIFICATION; SUBSTANCE USE DISORDERS; PRIMARY-HEALTH-CARE; NEUROKININ-1; RECEPTOR; COST-EFFECTIVENESS; HEAVY DRINKERS; DEPENDENCE; ADDICTION; MORTALITY; DRINKING;
D O I
10.1016/S0140-6736(19)31775-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Alcohol use disorders consist of disorders characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, especially in high-income and upper-middle-income countries; and are associated with high mortality and burden of disease, mainly due to medical consequences, such as liver cirrhosis or injury. Despite their high prevalence, alcohol use disorders are undertreated partly because of the high stigma associated with them, but also because of insufficient systematic screening in primary health care, although effective and cost-effective psychosocial and pharmacological interventions do exist. Primary health care should be responsible for most treatment, with routine screening for alcohol use, and the provision of a staggered treatment response, from brief advice to pharmacological treatment. Clinical interventions for these disorders should be embedded in a supportive environment, which can be bolstered by the creation of alcohol control policies aimed at reducing the overall level of consumption.
引用
收藏
页码:781 / 792
页数:12
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