Renal cell carcinoma in children: single-center experience

被引:12
作者
Helmy, Tamer [1 ]
Sarhan, Osama [1 ]
Sarhan, Mohamed [1 ]
El-Baz, Mahmoud [1 ]
Dawaba, Mohamed [1 ]
Ghali, Ahmad [1 ]
机构
[1] Mansoura Univ, Fac Med, Urol & Nephrol Ctr, Mansoura 35516, Egypt
关键词
Renal tumors; Renal adenocarcinoma; Hematuria; Radical nephrectomy; INSTITUTION; SERIES;
D O I
10.1016/j.jpedsurg.2009.02.073
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Purpose: The aim of the study was to report the experience with renal cell carcinoma (RCC) in children. Materials and Methods: We conducted a retrospective study on renal adenocarcinoma cases treated in our center between 1993 and 2008. The age limit was established at 15 years. We collected data on personal history, diagnostic age, sex, clinical presentation, tumor laterality, diagnostic procedure, and tumor stage according to TNM classification proposed by the International Union Against Cancer (2002), surgical technique, pathologic subtype, and outcome. Results: Six children were included in this study (4 girls and 2 boys) with a mean age of 9.5 years (range, 4-14 years). Tumor affected the right side in 4 patients and the left side in 2. Follow-up ranged from 9 to 140 months (mean, 85). Two patients were diagnosed as stage T1aN0M0, another was T1bN2M0, and 2 were T2N0M0, whereas the last one was T3N2M0. Radical nephrectomy was performed in 5 patients, whereas partial nephrectomy was adopted in one patient. The most common histologic subtype was translocation morphology RCC. One patient had local recurrence, whereas the other 5 are currently disease-free. Conclusion: Renal cell carcinoma is a rare histologic type of tumor in children, with certain features that differ from those in adults. In general, RCC in children tends to present later than Wilms' tumor and is usually associated with signs and/or symptoms of disease. In localized cases, the treatment of choice is radical nephrectomy. (c) 2009 Elsevier Inc. All rights reserved.
引用
收藏
页码:1750 / 1753
页数:4
相关论文
共 50 条
[21]   Renal Function Impairment Below Safety Limits Correlates With Cancer-specific Mortality in Localized Renal Cell Carcinoma: Results From a Single-center Study [J].
Antonelli, Alessandro ;
Palumbo, Carlotta ;
Sandri, Marco ;
Veccia, Alessandro ;
Furlan, Maria ;
Zamboni, Stefania ;
Francavilla, Simone ;
Zanotelli, Tiziano ;
Cozzoli, Alberto ;
Simeone, Claudio .
CLINICAL GENITOURINARY CANCER, 2020, 18 (04) :E360-E367
[22]   Renal Cell Carcinoma with Venous Tumor Thrombus: 15 Years of Experience in an Oncology Center [J].
Faria-Costa, Gabriel ;
Freitas, Rui ;
Braga, Isaac ;
Alzamora, Maria Ana ;
Magalhaes, Sanches ;
Carvalho, Joao ;
Correia, Jorge ;
Silva, Vitor Moreira ;
Lobo, Francisco ;
Henrique, Rui ;
Morais, Antonio .
JOURNAL OF CLINICAL MEDICINE, 2024, 13 (20)
[23]   Bladder Endometriosis: Diagnostic, Therapy, and Outcome of a Single-Center Experience [J].
Piriyev, Elvin ;
Schiermeier, Sven ;
Roemer, Thomas .
DIAGNOSTICS, 2025, 15 (04)
[24]   Operative management and outcomes in patients with myxomas: A single-center experience [J].
Alhasso, Ahmed Abdulfattah ;
Ahmed, Okba F. ;
Mohammed-Saeed, Dana H. ;
Kakamad, Fahmi H. ;
Almodhaffer, Saif S. ;
Zaid, Zaid A. ;
Abdullah, Hiwa O. ;
Ali, Razhan K. ;
Kakamad, Suhaib H. ;
Omar, Diyar A. ;
Abdalla, Berun A. ;
Mohammed, Shvan H. ;
Mustafa, Mohammed Q. .
FRONTIERS IN SURGERY, 2023, 10
[25]   Surgery in Bilateral Wilms Tumor-A Single-Center Experience [J].
de Souza, Fernanda Kelly Marques ;
Fanelli, Mayara Caroline Amorim ;
Duarte, Alexandre Alberto Barros ;
Alves, Maria Teresa de Seixas ;
Lederman, Henrique Manoel ;
Cypriano, Monica dos Santos ;
Abib, Simone de Campos Vieira .
CHILDREN-BASEL, 2023, 10 (11)
[26]   Factors Affecting Survival in Adrenocortical Cancers: Single-Center Experience [J].
Guven, Mehmet ;
Simsek, Mehmet ;
Tuzcu, Alpaslan Kemal .
TURKISH JOURNAL OF ENDOCRINOLOGY AND METABOLISM, 2020, 24 (03) :221-229
[27]   Diagnosis and Surgical Treatment of Nutcracker Syndrome: A Single-Center Experience [J].
Wang, Long ;
Yi, Lu ;
Yang, Luoyan ;
Liu, Ziting ;
Rao, Jianming ;
Liu, Longfei ;
Yang, Jinrui .
UROLOGY, 2009, 73 (04) :871-876
[28]   Comparison between laparoscopic and open radical nephrectomy for the treatment of primary renal tumors in children: Single-center experience over a 5-year period [J].
Romao, R. L. P. ;
Weber, B. ;
Gerstle, J. T. ;
Grant, R. ;
Salle, J. L. Pippi ;
Baegli, D. J. ;
Figueroa, V. H. ;
Braga, L. H. P. ;
Farhat, W. A. ;
Koyle, M. A. ;
Lorenzo, A. J. .
JOURNAL OF PEDIATRIC UROLOGY, 2014, 10 (03) :488-494
[29]   Sequential therapy and prognostic factors in metastatic renal cell carcinoma: single centre experience [J].
Esbah, Onur ;
Demirci, Umut ;
Helvaci, Kaan ;
Turkoz, Fatma Paksoy ;
Ekinci, Ahmet Siyar ;
Sonmez, Ozlem Uysal ;
Uyeturk, Umugul ;
'Turker, Ibrahim ;
Ozatli, Tahsin ;
Oksuzoglu, Berna .
JOURNAL OF BUON, 2014, 19 (04) :1062-1069
[30]   A Single-center Experience in Splenic Diffuse Red Pulp Lymphoma Diagnosis [J].
Julhakyan, Hunan L. ;
Al-Radi, L. S. ;
Moiseeva, T. N. ;
Danishyan, K. I. ;
Kovrigina, A. M. ;
Glebova, S. M. ;
Lugovskaya, S. A. ;
Dvirnik, V. N. ;
Khvastunova, A. N. ;
Yakutik, I. A. ;
Saychenko, V. G. .
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2016, 16 :S166-S169