Biocompatibility and Bioresorption of 3D-Printed Polylactide and Polyglycolide Tissue Membranes

被引：9

作者：

Kim, E., V ^{[1
]}

Petronyuk, Y. S. ^{[2
]}

Guseynov, N. A. ^{[1
]}

Tereshchuk, S., V ^{[4
]}

Popov, A. A. ^{[4
]}

Volkov, A. V. ^{[1
]}

Gorshenev, V. N. ^{[2
]}

Olkhov, A. A. ^{[2
]}

Levin, V. M. ^{[2
]}

Dymnikov, A. B. ^{[1
]}

Rodionov, V. E. ^{[1
]}

Tumanyan, G. A. ^{[1
]}

Ivashkevich, S. G. ^{[1
]}

Bonartsev, A. P. ^{[4
]}

Borozdkin, L. L. ^{[3
]}

机构：

[1] Peoples Friendship Univ Russia RUDN, Moscow, Russia

[2] Russian Acad Sci, NM Emanuel Inst Biochem Phys, Moscow, Russia

[3] IM Sechenov First Moscow State Med Univ, Minist Hlth Russian Federat, Sechenov Univ, Moscow, Russia

[4] Minist Def Russian Federat, NN Burdenko Main Mil Hosp, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2021年 / 170卷 / 03期

关键词：

barrier membrane; guided bone regeneration; 3D printing; polylactide; polyglycolide;

D O I：

10.1007/s10517-021-05066-x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We studied biocompatibility and bioresorption of 3D-printed polylactide and polyglycolide tissue membranes. Ultrasound microscopy and histological examination showed that membranes fabricated of a copolymer of lactic and glycolic acids in a mass ratio of 1:9 are bioresorbed and have good biocompatibility with soft tissues (connective tissue, adipose tissue, and epithelium). An important feature of the copolymer membranes, which differs them from pure polylactide membranes, is the formation of a thin fibrous capsule that did not interfere its destruction by the mechanism of hydrolytic resorption.

引用

页码：356 / 359

页数：4

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