In situ methotrexate injection for treatment of recurrent endometriotic cysts

被引：30

作者：

Agostini, Aubert ^{[1
]}

De Lapparent, Thomas ^{[1
]}

Collette, Emmanuelle ^{[1
]}

Capelle, Mariane ^{[1
]}

Cravello, Ludovic ^{[1
]}

Blanc, Bemard ^{[1
]}

机构：

[1] Hop Conception, Gynecol Serv, F-13385 Marseille, France

来源：

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 2007年 / 130卷 / 01期

关键词：

methotrexate; ovarian endometrioma; recurrence;

D O I：

10.1016/j.ejogrb.2006.01.015

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: Ovarian endometrioma recurrence is frequent. Conventional treatment of ovarian endometrioma is by surgical cystectomy. We proposed an alternative medical treatment for recurrent ovarian endometrioma: cyst aspiration followed by in situ methotrexate injection. Study design: From January 2002 to May 2003, 14 patients with recurrent homolateral ovarian endometrioma underwent transvaginal ultrasound guided cyst puncture and aspiration followed by methotrexate injection, whilst under general anasthesia. Recurrence rate during follow up was evaluated. Results: No complication was reported. After a mean follow up of 20 5 month (min: 13, max: 29), four recurrences were diagnosed (28.6%). Two asymptomatic recurrences were not treated and two painful recurrences underwent a second cyst drainage with methotrexate injection. Conclusions: In situ methotrexate injection is a simple, effective and an interesting alternative to surgical treatment in women with recurrent homolateral ovarian endometrioma. (C) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：129 / 131

页数：3

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