Nasal dermoplasty for Japanese hereditary hemorrhagic telangiectasia

被引:9
作者
Ichimura, Keiichi [1 ]
Tanaka, Hidetaka [1 ]
Yamamoto, Yoshinori [1 ]
Nakamura, Ken-ichi [1 ]
机构
[1] Jichi Med Univ, Sch Med, Dept Otolaryngol Head & Neck Surg, Shimotsuke, Tochigi 3290498, Japan
关键词
hereditary hemorrhagic telangiectasis; epistaxis; nasal dermoplasty;
D O I
10.1016/j.anl.2006.03.001
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: While generally considered an effective treatment for moderate to severe epistaxis in hereditary hemorrhagic telangiectasia (HHT), nasal dermoplasty (ND) has not been well established in Japan. This prompted the present Japanese assessment of clinical efficacy and patient satisfaction following this procedure. Methods: Retrospective analysis of clinical records of 15 patients with HHT undergoing ND between August 1991 and May 2004 and survey of these patients as to postsurgical conditions. Main outcome measures were skin graft "take" frequency after surgery (all patients), reported patient satisfaction (eight recent patients), and reported volume and frequency of epistaxis after versus before surgery (eight recent patients). Results: Graft take rate was 100%. Most patients experienced reduced frequency and volume of bleeding. One patient required an additional operation, total closure of the external nares, 2 years later. Overall patients felt satisfied with ND, experiencing less nasal obstruction than expected. Conclusions: ND is effective in Japanese patients with moderate and severe nasal bleeding from HHT, reducing their risk of bleeding. (C) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:423 / 428
页数:6
相关论文
共 26 条
  • [1] Hereditary haemorrhagic telangiectasia (Osier-Weber-Rendu syndrome): a view from the 21st century
    Begbie, ME
    Wallace, GMF
    Shovlin, CL
    [J]. POSTGRADUATE MEDICAL JOURNAL, 2003, 79 (927) : 18 - 24
  • [2] BRAVERMAN IM, 1990, J INVEST DERMATOL, V95, P442
  • [3] Genetic epidemiology of hereditary hemorrhagic telangiectasia in a local community in the northern part of Japan
    Dakeishi, M
    Shioya, T
    Wada, Y
    Shindo, T
    Otaka, K
    Manabe, M
    Nozaki, J
    Inoue, S
    Koizumi, A
    [J]. HUMAN MUTATION, 2002, 19 (02) : 140 - 148
  • [4] Outcome of septal dermoplasty in patients with hereditary hemorrhagic telangiectasia
    Fiorella, ML
    Ross, D
    Henderson, KJ
    White, RI
    [J]. LARYNGOSCOPE, 2005, 115 (02) : 301 - 305
  • [5] Morphology and distribution of nasal telangiectasia in HHT-patients with epistaxis
    Folz, BJ
    Wollstein, AC
    Lippert, BM
    Werner, JA
    [J]. AMERICAN JOURNAL OF RHINOLOGY, 2005, 19 (01): : 65 - 70
  • [6] GLUCKMAN JL, 1994, LARYNGOSCOPE, V104, P1174
  • [7] The effect of treatment for epistaxis secondary to hereditary hemorrhagic telangiectasia
    Hitchings, AE
    Lennox, PA
    Lund, VJ
    Howard, DJ
    [J]. AMERICAN JOURNAL OF RHINOLOGY, 2005, 19 (01): : 75 - 78
  • [8] ICHIMURA K, 1994, PRACTICA OTOLOGICA, V87, P895
  • [9] JAHNKE V, 1970, ARCHIV OTOLARYNGOL, V91, P262
  • [10] Hormonal and antihormonal therapy for epistaxis in hereditary hemorrhagic telangiectasia
    Jameson, JJ
    Cave, DR
    [J]. LARYNGOSCOPE, 2004, 114 (04) : 705 - 709