Case Report: Rapidly Progressive Interstitial Lung Disease in A Pregnant Patient With Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis

被引:6
作者
Chen, Cuihong [1 ]
Chen, Yulan [1 ]
Huang, Qin [1 ]
Hu, Qiu [1 ]
Hong, Xiaoping [1 ]
机构
[1] Southern Univ Sci & Technol, Affiliated Hosp 1, Jinan Univ, Clin Med Coll 2,Dept Rheumatol & Immunol,Shenzhen, Shenzhen, Peoples R China
来源
FRONTIERS IN IMMUNOLOGY | 2021年 / 12卷
关键词
clinically amyopathic dermatomyositis; anti-melanoma differentiation-associated gene 5; rapidly progressive interstitial lung disease; pregnancy; treatment; CLINICALLY AMYOPATHIC DERMATOMYOSITIS; ANTI-MDA5; ANTIBODY; AUTOANTIBODIES; THERAPY; RISK;
D O I
10.3389/fimmu.2021.625495
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Dermatomyositis occurs extremely rarely during pregnancy. A number of studies in the published literature have documented how the outcome of pregnancy is poor for both mother and fetus. The present case study reports on a patient who was diagnosed with clinically amyopathic dermatomyositis complicated by interstitial lung disease during pregnancy, and was successfully treated with a combined immunosuppressant regimen. To the best of the authors' knowledge, this is the first case study detailing how a pregnant woman with clinically amyopathic dermatomyositis with positive anti-melanoma differentiation-associated gene 5 antibody achieved complete remission after early intervention of combined immunosuppressive therapy without residual pulmonary interstitial changes.
引用
收藏
页数:6
相关论文
共 32 条
  • [1] Akalin Tayfun, 2016, Case Rep Obstet Gynecol, V2016, P6430156, DOI 10.1155/2016/6430156
  • [2] Amer Thoracic Soc, 2000, AM J RESP CRIT CARE, V161, P646
  • [3] Aoki Akiko, JAPANESE J CLIN IMMU, V23, P124, DOI [10.2177/jsci.23.124, DOI 10.2177/JSCI.23.124]
  • [4] Awatef Kelati, 2016, Pan Afr Med J, V23, P117, DOI 10.11604/pamj.2016.23.117.9198
  • [5] Obesity and COVID-19 Severity in a Designated Hospital in Shenzhen, China
    Cai, Qingxian
    Chen, Fengjuan
    Wang, Tao
    Luo, Fang
    Liu, Xiaohui
    Wu, Qikai
    He, Qing
    Wang, Zhaoqin
    Liu, Yingxia
    Liu, Lei
    Chen, Jun
    Xu, Lin
    [J]. DIABETES CARE, 2020, 43 (07) : 1392 - 1398
  • [6] Treatment of clinically amyopathic dermatomyositis in adults: a systematic review
    Callander, J.
    Robson, Y.
    Ingram, J.
    Piguet, V.
    [J]. BRITISH JOURNAL OF DERMATOLOGY, 2018, 179 (06) : 1248 - 1255
  • [7] Utility of Anti-Melanoma Differentiation-Associated Gene 5 Antibody Measurement in Identifying Patients With Dermatomyositis and a High Risk for Developing Rapidly Progressive Interstitial Lung Disease: A Review of the Literature and a Meta-Analysis
    Chen, Zhiyong
    Cao, Mengshu
    Nieves Plana, Maria
    Liang, Jun
    Cai, Hourong
    Kuwana, Masataka
    Sun, Lingyun
    [J]. ARTHRITIS CARE & RESEARCH, 2013, 65 (08) : 1316 - 1324
  • [8] Rapidly progressive interstitial lung disease due to anti-melanoma differentiation associated protein-5 requiring a bilateral lung transplant, and complicated by kennel cough
    Deitchman, Andrew R.
    Kalchiem-Dekel, Or
    Todd, Nevins
    Reed, Robert M.
    [J]. RESPIRATORY MEDICINE CASE REPORTS, 2019, 28
  • [9] A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis sine myositis): A missing link within the spectrum of the idiopathic inflammatory myopathies
    Gerami, P
    Schope, JM
    McDonald, L
    Walling, HW
    Sontheimer, RD
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2006, 54 (04) : 597 - 613
  • [10] Anti-MDA5 antibody, ferritin and IL-18 are useful for the evaluation of response to treatment in interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis
    Gono, Takahisa
    Sato, Shinji
    Kawaguchi, Yasushi
    Kuwana, Masataka
    Hanaoka, Masanori
    Katsumata, Yasuhiro
    Takagi, Kae
    Baba, Sayumi
    Okamoto, Yuko
    Ota, Yuko
    Yamanaka, Hisashi
    [J]. RHEUMATOLOGY, 2012, 51 (09) : 1563 - 1570