Treatment of idiopathic sclerosing inflammation of the orbit (myositis) with infliximab

被引:24
作者
Sahlin, Sven [1 ]
Lignell, Borje [2 ]
Williams, Maria [2 ]
Dastmalchi, Maryam [3 ]
Orrego, Abiel [4 ]
机构
[1] St Eriks Eye Hosp, Karolinska Inst, S-11282 Stockholm, Sweden
[2] AHS, Mariehamn, Aland, Finland
[3] Karolinska Hosp & Inst, Dept Rheumatol, Stockholm, Sweden
[4] Karolinska Hosp & Inst, Dept Pathol, Stockholm, Sweden
关键词
idiopathic orbital inflammation; infliximab; myositis; sclerosing orbital inflammation;
D O I
10.1111/j.1755-3768.2008.01320.x
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: We report the successful use of infliximab in a young patient with idiopathic sclerosing orbital inflammation (myositis). Methods: We describe the patient's medical records and review the literature. Results: Idiopathic myositis in this patient could not be satisfactorily treated with corticosteroids or chemotherapy. Biopsy showed sclerosing orbital inflammation. The patient had a prompt and sustained response with infliximab and methotrexate treatment. Conclusions: Infliximab and methotrexate might be considered in patients with idiopathic sclerosing orbital inflammation (myositis).
引用
收藏
页码:906 / 908
页数:3
相关论文
共 11 条
[1]  
Adams AB, 2005, J RHEUMATOL, V32, P1374
[2]   Decreasing TNF-α results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis [J].
Chen, Kemin ;
Wei, Yongzhong ;
Sharp, Gordon C. ;
Braley-Mullen, Helen .
JOURNAL OF LEUKOCYTE BIOLOGY, 2007, 81 (01) :306-314
[3]   Does safety make a difference in selecting the right TNF antagonist? [J].
Fleischmann, R ;
Yocum, D .
ARTHRITIS RESEARCH & THERAPY, 2004, 6 (Suppl 2) :S12-S18
[4]   Treatment of recalcitrant idiopathic orbital inflammation (chronic orbital myositis) with infliximab [J].
Garrity, JA ;
Coleman, AW ;
Matteson, EL ;
Eggenberger, ER ;
Waitzman, DM .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2004, 138 (06) :925-930
[5]   Nonthyroid causes of extraocular muscle disease [J].
Lacey, B ;
Chang, W ;
Rootman, J .
SURVEY OF OPHTHALMOLOGY, 1999, 44 (03) :187-213
[6]   Magnetic resonance imaging and ultrasound measurements of extraocular muscles in thyroid-associated ophthalmopathy at different stages of the disease [J].
Lennerstrand, Gunnar ;
Tian, Suna ;
Isberg, Bengt ;
Hogbeck, Irene Landau ;
Bolzani, Roberto ;
Tallstedt, Leif ;
Schworm, Hermann .
ACTA OPHTHALMOLOGICA SCANDINAVICA, 2007, 85 (02) :192-201
[7]  
MCCARTHY JM, 1993, MODERN PATHOL, V6, P581
[8]  
ROOTMAN J, 1994, OPHTHALMOLOGY, V101, P570
[9]   Infliximab therapy for the treatment of refractory ocular inflammatory disease [J].
Sobrin, Lucia ;
Kim, Eva C. ;
Christen, William ;
Papadaki, Thekla ;
Letko, Erik ;
Foster, C. Stephen .
ARCHIVES OF OPHTHALMOLOGY, 2007, 125 (07) :895-900
[10]  
WHITE VA, 1994, PRINCIPLES PRACTICE, V4, P2316