Sheehan's syndrome with pancytopenia-complete recovery after hormone replacement (case series with review)

被引：33

作者：

Laway, Bashir Ahmad ^{[1
]}

Bhat, Javid Rasool ^{[2
]}

Mir, Shahnaz Ahmad ^{[1
]}

Khan, Raja Sultan Zaman ^{[1
]}

Lone, Mohd Iqbal ^{[3
]}

Zargar, Abdul Hamid ^{[1
]}

机构：

[1] Sherikashmir Inst Med Sci, Dept Endocrinol, Srinagar, Jammu & Kashmir, India

[2] Sherikashmir Inst Med Sci, Dept Clin Hematol, Srinagar, Jammu & Kashmir, India

[3] Sherikashmir Inst Med Sci, Dept Pathol, Srinagar, Jammu & Kashmir, India

来源：

ANNALS OF HEMATOLOGY | 2010年 / 89卷 / 03期

关键词：

Sheehan's syndrome; Pancytopenia; Hypopituitarism; Post partumhemorrhage; MARROW APLASIA; HYPOPITUITARISM; THERAPY;

D O I：

10.1007/s00277-009-0804-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Reports of pancytopenia in patients with Sheehan's syndrome are rare, because the disorder is not commonly seen in western countries. A case series of pancytopenia in three patients of Sheehan's syndrome is presented. Three women aged 22, 30, and 34 years developed Sheehan's syndrome preceded by post partum hemorrhage. During investigations, they were found to have pancytopenia with hypocellular marrow. Treatment with thyroxine and glucocorticoids resulted in complete recovery after attaining euthyroid and eucortisolemic state. Review of literature revealed the rarity of the disorder, with only four cases reported so far. Multiple anterior pituitary hormone deficiencies in Sheehan's syndrome are responsible for pancytopenia; replacement of thyroid and cortisol hormones results in complete recovery.

引用

页码：305 / 308

页数：4

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