Relationship between pediatric obesity and otitis media with effusion

被引:21
作者
Lee, Sun Kyu [1 ]
Yeo, Seung Geun [1 ]
机构
[1] Kyung Hee Univ, Coll Med, Dept Otorhinolaryngol, Seoul 130702, South Korea
关键词
TUMOR-NECROSIS-FACTOR; CHORDA TYMPANI NERVE; DIET-INDUCED THERMOGENESIS; MIDDLE-EAR EFFUSIONS; FACTOR-ALPHA; GUSTATORY FUNCTION; ADIPOSE-TISSUE; TASTE FUNCTION; CYTOKINE; EXPRESSION;
D O I
10.1007/s11882-009-0069-3
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Although eustachian tube dysfunction and bacterial infection have been shown to cause otitis media with effusion (OME), other etiologies are possible. One of the most common medical conditions in children is obesity, which can have effects throughout the body. Little is known, however, about the relationship between obesity and OME. Obesity may result in altered cytokine expression, gastroesophageal reflux disease, or fat accumulation, all of which may contribute to OME. Conversely, OME may induce taste changes through middle ear cavity inflammation, thus contributing to obesity. A similar pattern of taste change has been shown in patients with gustatory nerve anesthesia. Further research on the relationship between obesity and OME may help to determine the exact etiology of OME and contribute to our knowledge about the causes of obesity.
引用
收藏
页码:465 / 472
页数:8
相关论文
共 48 条
[1]   Linking Laryngopharyngeal Reflux to Otitis Media with Effusion: Pepsinogen Study of Adenoid Tissue and Middle Ear Fluid [J].
Al-Saab, Fahad ;
Manoukian, John J. ;
Al-Sabah, Basel ;
Almot, Sawsan ;
Nguyen, Lily H. P. ;
Tewfik, Ted L. ;
Daniel, Sam J. ;
Schloss, Melvin D. ;
Hamid, Qutayba A. .
JOURNAL OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2008, 37 (04) :565-571
[2]   Cytokine analysis of middle ear effusions during acute otitis media: Significant reduction in tumor necrosis factor alpha concentrations correlates with bacterial eradication [J].
Barzilai, A ;
Dekel, B ;
Dagan, R ;
Passwell, JH ;
Leibovitz, E .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1999, 18 (03) :301-303
[3]   Role of allergy in eustachian tube blockage and otitis media with effusion: A review [J].
Bernstein, JM .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1996, 114 (04) :562-568
[4]   The chronic inflammatory hypothesis for the morbidity associated with morbid obesity: Implications and effects of weight loss [J].
Cottam, DR ;
Mattar, SG ;
Barinas-Mitchell, E ;
Eid, G ;
Kuller, L ;
Kelley, DE ;
Schauer, PR .
OBESITY SURGERY, 2004, 14 (05) :589-600
[5]   Tumor necrosis factor during experimental lipopolysaccharide-induced otitis media [J].
DeMaria, TF ;
Murwin, DM .
LARYNGOSCOPE, 1997, 107 (03) :369-372
[6]   Food "cravings" and the acute effects of alprazolam on food intake in women with premenstrual dysphoric disorder [J].
Evans, SM ;
Foltin, RW ;
Fischman, MW .
APPETITE, 1999, 32 (03) :331-349
[7]   Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and Adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans [J].
Fain, JN ;
Madan, AK ;
Hiler, ML ;
Cheema, P ;
Bahouth, SW .
ENDOCRINOLOGY, 2004, 145 (05) :2273-2282
[8]   Adipose tissue, adipokines, and inflammation [J].
Fantuzzi, G .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2005, 115 (05) :911-919
[9]   Cause-specific excess deaths associated with underweight, overweight, and obesity [J].
Flegal, Katherine M. ;
Graubard, Barry I. ;
Williamson, David F. ;
Gail, Mitchell H. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (17) :2028-2037
[10]   Histopathological changes of chorda tympani in chronic otitis media [J].
Gedikli, O ;
Dogru, H ;
Aydin, G ;
Tüz, M ;
Uygur, K ;
Sari, L .
LARYNGOSCOPE, 2001, 111 (04) :724-727