A Catalytic, Oxidative Synthesis of Olivetol, Methyl Olivetolate and Orthogonally Protected Methyl Ether Derivatives

被引：8

作者：

Hurem, David ^{[1
]}

Macphail, Benjamin J. ^{[2
]}

Carlini, Rina ^{[2
]}

Lewis, Jason ^{[2
]}

McNulty, James ^{[1
]}

机构：

[1] McMaster Univ, Dept Chem & Chem Biol, 1280 Main St West, Hamilton, ON L8S 4M1, Canada

[2] Rapid Dose Therapeut, 1121 Walkers Line,Suite 3, Burlington, ON L7N 2G4, Canada

来源：

SYNOPEN | 2021年 / 05卷 / 01期

关键词：

olivetol; olivetolic acid; aromatization; catalysis; oxidation; polyketide; meroterpenoid; PRACTICAL SYNTHESIS; MEDICAL MARIJUANA; CANNABIDIOL; ACID; PHENOLS;

D O I：

10.1055/a-1440-9732

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Olivetol, methyl olivetolate and a series of orthogonally protected methyl ether derivatives were synthesized from commonly available precursors using an atom-economical, catalytic oxidative aromatization process.

引用

页码：86 / 90

页数：5

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