A First-Generation Haplotype Map of Maize

被引：558
作者：
Gore, Michael A. [1 ,2 ,3 ]
Chia, Jer-Ming [4 ]
Elshire, Robert J. [3 ]
Sun, Qi [5 ]
Ersoz, Elhan S. [3 ]
Hurwitz, Bonnie L. [4 ]
Peiffer, Jason A. [2 ]
McMullen, Michael D. [1 ,6 ]
Grills, George S. [7 ]
Ross-Ibarra, Jeffrey [8 ]
Ware, Doreen H. [1 ,4 ]
Buckler, Edward S. [1 ,2 ,3 ]
机构：
[1] Cornell Univ, USDA ARS, Ithaca, NY 14853 USA
[2] Cornell Univ, Dept Genet & Plant Breeding, Ithaca, NY 14853 USA
[3] Cornell Univ, Inst Genom Divers, Ithaca, NY 14853 USA
[4] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
[5] Cornell Univ, Computat Biol Serv Unit, Ithaca, NY 14853 USA
[6] Univ Missouri, Div Plant Sci, Columbia, MO 65211 USA
[7] Cornell Univ, Inst Biotechnol & Life Sci Technol, Ithaca, NY 14853 USA
[8] Univ Calif Davis, Dept Plant Sci, Davis, CA 95616 USA
来源：
SCIENCE | 2009年 / 326卷 / 5956期
基金：
美国国家科学基金会;
关键词：
ARTIFICIAL SELECTION; ARABIDOPSIS-THALIANA; GENOME; POPULATION; DOMESTICATION; DIVERSITY; DNA; POLYMORPHISM; DIVERGENCE; ZEA;
D O I：
10.1126/science.1177837
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Maize is an important crop species of high genetic diversity. We identified and genotyped several million sequence polymorphisms among 27 diverse maize inbred lines and discovered that the genome was characterized by highly divergent haplotypes and showed 10- to 30-fold variation in recombination rates. Most chromosomes have pericentromeric regions with highly suppressed recombination that appear to have influenced the effectiveness of selection during maize inbred development and may be a major component of heterosis. We found hundreds of selective sweeps and highly differentiated regions that probably contain loci that are key to geographic adaptation. This survey of genetic diversity provides a foundation for uniting breeding efforts across the world and for dissecting complex traits through genome-wide association studies.
引用
收藏
页码：1115 / 1117
页数：3
相关论文
共 22 条
  • [1] Population genomics:: Whole-genome analysis of polymorphism and divergence in Drosophila simulans
    Begun, David J.
    Holloway, Alisha K.
    Stevens, Kristian
    Hillier, LaDeana W.
    Poh, Yu-Ping
    Hahn, Matthew W.
    Nista, Phillip M.
    Jones, Corbin D.
    Kern, Andrew D.
    Dewey, Colin N.
    Pachter, Lior
    Myers, Eugene
    Langley, Charles H.
    [J]. PLOS BIOLOGY, 2007, 5 (11) : 2534 - 2559
  • [2] The Genetic Architecture of Maize Flowering Time
    Buckler, Edward S.
    Holland, James B.
    Bradbury, Peter J.
    Acharya, Charlotte B.
    Brown, Patrick J.
    Browne, Chris
    Ersoz, Elhan
    Flint-Garcia, Sherry
    Garcia, Arturo
    Glaubitz, Jeffrey C.
    Goodman, Major M.
    Harjes, Carlos
    Guill, Kate
    Kroon, Dallas E.
    Larsson, Sara
    Lepak, Nicholas K.
    Li, Huihui
    Mitchell, Sharon E.
    Pressoir, Gael
    Peiffer, Jason A.
    Rosas, Marco Oropeza
    Rocheford, Torbert R.
    Cinta Romay, M.
    Romero, Susan
    Salvo, Stella
    Sanchez Villeda, Hector
    da Silva, H. Sofia
    Sun, Qi
    Tian, Feng
    Upadyayula, Narasimham
    Ware, Doreen
    Yates, Heather
    Yu, Jianming
    Zhang, Zhiwu
    Kresovich, Stephen
    McMullen, Michael D.
    [J]. SCIENCE, 2009, 325 (5941) : 714 - 718
  • [3] Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana
    Clark, Richard M.
    Schweikert, Gabriele
    Toomajian, Christopher
    Ossowski, Stephan
    Zeller, Georg
    Shinn, Paul
    Warthmann, Norman
    Hu, Tina T.
    Fu, Glenn
    Hinds, David A.
    Chen, Huaming
    Frazer, Kelly A.
    Huson, Daniel H.
    Schoelkopf, Bernhard
    Nordborg, Magnus
    Raetsch, Gunnar
    Ecker, Joseph R.
    Weigel, Detlef
    [J]. SCIENCE, 2007, 317 (5836) : 338 - 342
  • [4] Maize association population: a high-resolution platform for quantitative trait locus dissection
    Flint-Garcia, SA
    Thuillet, AC
    Yu, JM
    Pressoir, G
    Romero, SM
    Mitchell, SE
    Doebley, J
    Kresovich, S
    Goodman, MM
    Buckler, ES
    [J]. PLANT JOURNAL, 2005, 44 (06) : 1054 - 1064
  • [5] Intraspecific violation of genetic colinearity and its implications in maize
    Fu, HH
    Dooner, HK
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (14) : 9573 - 9578
  • [6] Population genetic analysis of shotgun assemblies of genomic sequences from multiple individuals
    Hellmann, Ines
    Mang, Yuan
    Gu, Zhiping
    Li, Peter
    de la Vega, Francisco M.
    Clark, Andrew G.
    Nielsen, Rasmus
    [J]. GENOME RESEARCH, 2008, 18 (07) : 1020 - 1029
  • [7] The centromere paradox: Stable inheritance with rapidly evolving DNA
    Henikoff, S
    Ahmad, K
    Malik, HS
    [J]. SCIENCE, 2001, 293 (5532) : 1098 - 1102
  • [8] High DNA sequence diversity in pericentromeric genes of the plant Arabidopsis lyrata
    Kawabe, Akira
    Forrest, Alan
    Wright, Stephen I.
    Charlesworth, Deborah
    [J]. GENETICS, 2008, 179 (02) : 985 - 995
  • [9] Recombination and linkage disequilibrium in Arabidopsis thaliana
    Kim, Sung
    Plagnol, Vincent
    Hu, Tina T.
    Toomajian, Christopher
    Clark, Richard M.
    Ossowski, Stephan
    Ecker, Joseph R.
    Weigel, Detlef
    Nordborg, Magnus
    [J]. NATURE GENETICS, 2007, 39 (09) : 1151 - 1155
  • [10] Genetic Properties of the Maize Nested Association Mapping Population
    McMullen, Michael D.
    Kresovich, Stephen
    Villeda, Hector Sanchez
    Bradbury, Peter
    Li, Huihui
    Sun, Qi
    Flint-Garcia, Sherry
    Thornsberry, Jeffry
    Acharya, Charlotte
    Bottoms, Christopher
    Brown, Patrick
    Browne, Chris
    Eller, Magen
    Guill, Kate
    Harjes, Carlos
    Kroon, Dallas
    Lepak, Nick
    Mitchell, Sharon E.
    Peterson, Brooke
    Pressoir, Gael
    Romero, Susan
    Rosas, Marco Oropeza
    Salvo, Stella
    Yates, Heather
    Hanson, Mark
    Jones, Elizabeth
    Smith, Stephen
    Glaubitz, Jeffrey C.
    Goodman, Major
    Ware, Doreen
    Holland, James B.
    Buckler, Edward S.
    [J]. SCIENCE, 2009, 325 (5941) : 737 - 740
123