Synthesis of antimicrobial 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines

被引：79

作者：

Kotharkar, Sandeep A. ^{[1
]}

Shinde, Devanand B. ^{[1
]}

机构：

[1] Marathwada Univ, Dept Chem Technol, Aurangabad 431004, Maharashtra, India

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 24期

关键词：

quinoxallinones; antimicrobial activity;

D O I：

10.1016/j.bmcl.2006.09.040

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new series of 2,9,10-trisubstituted-6-oxo-7,12-dihydro-chromeno[3,4-b]quinoxalines was synthesized and submitted to antibacterial and antifungal activities. Result of the antimicrobial screening showed the compound 4j being the most effective among the various treatments in antimicrobial screening. Compounds 4c, 4d, 4k, and 4I showed moderate activity against the microorganisms tested. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：6181 / 6184

页数：4

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