STDP rule endowed with the BCM sliding threshold accounts for hippocampal heterosynaptic plasticity

被引:32
作者
Benuskova, Lubica [1 ]
Abraham, Wickliffe C.
机构
[1] Auckland Univ Technol, Knowledge Engn & Discovery Res Inst, Auckland, New Zealand
[2] Comenius Univ, Fac Math Phys & Informat, Dept Appl Informat, Bratislava 81806, Slovakia
[3] Univ Otago, Dept Psychol, Dunedin, New Zealand
关键词
heterosynaptic plasticity; metaplasticity; STDP; sliding BCM threshold;
D O I
10.1007/s10827-006-0002-x
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We have combined the nearest neighbour additive spike-timing-dependent plasticity (STDP) rule with the Bienenstock, Cooper and Munro (BCM) sliding modification threshold in a computational model of heterosynaptic plasticity in the hippocampal dentate gyrus. As a result we can reproduce (1) homosynaptic long-term potentiation of the tetanized input, and (2) heterosynaptic long-term depression of the untetanized input, as observed in real experiments.
引用
收藏
页码:129 / 133
页数:5
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