Time-resolved mid-infrared spectroscopy: methods and biological applications

被引：25
作者：
Slayton, RM
Anfinrud, PA
机构：
[1] Dept. of Chem. and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge
来源：
CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 05期
关键词：
D O I：
10.1016/S0959-440X(97)80083-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Recent developments in time-resolved infrared spectroscopy have paved the way to probe transient intermediates with a high degree of functional group specificity on timescales as short as femtoseconds. This capability has been exploited in studies of biophysical phenomena ranging from protein folding/unfolding to ligand migration in proteins. (C) Current Biology Ltd ISSN 0959-440X
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页码：717 / 721
页数：5
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