EGFR mutations in exons 18-21 in sporadic breast cancer

被引:27
作者
Generali, D.
Leek, R.
Fox, S. B.
Moore, J. W.
Taylor, C.
Chambers, P.
Harris, A. L. [1 ]
机构
[1] Weatherall Inst Mol Med, Mol Oncol Labs, Oxford, England
[2] Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Lab Sci, Oxford OX3 9DU, England
[3] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia
[4] St James Univ Hosp, CRUK, Mutat Detect Facil, Leeds, W Yorkshire, England
关键词
D O I
10.1093/annonc/mdl322
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:203 / U7
页数:3
相关论文
共 6 条
[1]  
BASELGA J, 2005, J CLIN ONCOL
[2]   EGFR gene amplification in breast cancer:: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations [J].
Bhargava, R ;
Gerald, WL ;
Li, AR ;
Pan, QL ;
Lal, P ;
Ladanyi, M ;
Chen, BY .
MODERN PATHOLOGY, 2005, 18 (08) :1027-1033
[3]   Somatic mutations of ERBB2 kinase domain in gastric, colorectal, and breast carcinomas [J].
Lee, JW ;
Soung, YH ;
Seo, SH ;
Kim, SY ;
Park, CH ;
Wang, YP ;
Park, K ;
Nam, SW ;
Park, WS ;
Kim, SH ;
Lee, JY ;
Yoo, NJ ;
Lee, SH .
CLINICAL CANCER RESEARCH, 2006, 12 (01) :57-61
[4]   Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib [J].
Lynch, TJ ;
Bell, DW ;
Sordella, R ;
Gurubhagavatula, S ;
Okimoto, RA ;
Brannigan, BW ;
Harris, PL ;
Haserlat, SM ;
Supko, JG ;
Haluska, FG ;
Louis, DN ;
Christiani, DC ;
Settleman, J ;
Haber, DA .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (21) :2129-2139
[5]   Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: A double-blind placebo-controlled phase II randomised trial [J].
Polychronis, A ;
Sinnett, HD ;
Hadjiminas, D ;
Singhal, H ;
Monsi, JL ;
Shivapatham, D ;
Shousha, S ;
Jiang, J ;
Peston, D ;
Barrett, N ;
Vigushin, D ;
Morrison, K ;
Beresford, E ;
Ali, S ;
Slade, MJ ;
Coombes, RC .
LANCET ONCOLOGY, 2005, 6 (06) :383-391
[6]   Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors [J].
Weber, F ;
Fukino, K ;
Sawada, T ;
Williams, N ;
Sweet, K ;
Brena, RM ;
Plass, C ;
Caldes, T ;
Mutter, GL ;
Villalona-Calero, MA ;
Eng, C .
BRITISH JOURNAL OF CANCER, 2005, 92 (10) :1922-1926