Probing Macrophage Activity with Carbon-Nanotube Sensors

被引:18
作者
Heller, Iddo [1 ]
Smaal, Wiljan T. T. [1 ]
Lemay, Serge G. [1 ]
Dekker, Cees [1 ]
机构
[1] Delft Univ Technol, Sect Mol Biophys, Kavli Inst NanoSci, NL-2628 CJ Delft, Netherlands
关键词
biosensors; carbon nanotubes; cells; electrochemistry; field-effect transistors; REACTIVE OXYGEN; REAL-TIME; VESICULAR EXOCYTOSIS; METAL NANOPARTICLES; OXIDATIVE STRESS; TRANSISTORS; BIOSENSORS; ELECTROCHEMISTRY; NANOELECTRODES; MECHANISM;
D O I
10.1002/smll.200900823
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Sensors made from single carbon nanotubes have great potential to function as nanometer-scale electrical probes for single-cell studies (see image). A nanotube is used both as an amperometric and a transistor sensor and signals are correlated with the activity of a macrophage cell located on the device. In addition, the stability and sensitivity issues are highlighted and ways to enhance nanotube sensors are demonstrated. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:2528 / 2532
页数:5
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