FOXP1 suppresses the endothelial NLRP3 inflammasome

被引：3
|
作者：
Lim, Gregory B.
机构：
[1] Nature Reviews Cardiology,
来源：
NATURE REVIEWS CARDIOLOGY | 2019年 / 16卷 / 10期
关键词：
D O I：
10.1038/s41569-019-0252-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The transcription factor FOXP1 downregulates activation of the endothelial NLRP3 inflammasome and suppresses vascular inflammation, protecting against atherosclerosis. Upregulation of FOXP1 expression is a novel anti-atherogenic effect of simvastatin.
引用
收藏
页码：578 / 579
页数：2
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