Adult Cerebellopontine Angle Medulloblastoma Originating in the Pons Mimicking Focal Brainstem Tumor

被引:7
作者
Yoshimura, Junichi [1 ]
Nishiyama, Kenichi [1 ]
Fukuda, Masafumi [1 ]
Watanabe, Masaki [2 ]
Igarashi, Hironaka [2 ]
Fujii, Yukihiko [1 ,2 ]
机构
[1] Niigata Univ, Brain Res Inst, Dept Neurosurg, Niigata 9518585, Japan
[2] Niigata Univ, Brain Res Inst, Ctr Integrated Human Brain Sci, Niigata 9518585, Japan
关键词
Brainstem tumor; medulloblastoma; primitive neuroectodermal tumor; cerebellopontine angle; magnetic resonance image; PRIMITIVE NEUROECTODERMAL TUMORS;
D O I
10.1111/j.1552-6569.2008.00298.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We herein report a rare case of cerebellopontine angle (CPA) medulloblastoma originating in the brainstem that demonstrated a very unusual clinical presentation and radiological appearances. A 25-year-old female was admitted to our hospital with a right hearing disturbance and a right facial palsy. A small non-enhanced lesion having minimal mass effect in the right CPA was identified by using a 1.5-tesla-MR system, whose size remained almost unchanged a year. The 3-tesla MR images revealed that the precise region was in the right side of the tegmentum of the lower pons to the inferior cerebellar peduncle and the flocculus. MR spectroscopic images using a 3-tesla system revealed a high ratio of choline-to-N-acetylaspartate in the region of interest in comparison to the contra-lateral side. Craniotomy and biopsy were performed. The histopathological diagnosis was medulloblastoma. The patient received craniospinal irradiation and chemotherapy, and achieved complete remission by the time of the follow-up MR images. She is now doing well with a full recovery of the right facial palsy. MR spectroscopic imaging is considered to be quite useful for the management of this rare type of brainstem tumor. J Neuroimaging 2009;19:385-387.
引用
收藏
页码:385 / 387
页数:3
相关论文
共 6 条
  • [1] Intra-axial endophytic primitive neuroectodermal tumors in the pons: Clinical, radiological, and immunohistochemical aspects in four children
    Behnke, J
    Mursch, K
    Bruck, W
    Christen, HJ
    Markakis, E
    [J]. CHILDS NERVOUS SYSTEM, 1996, 12 (03) : 125 - 129
  • [2] *COMM BRAIN TUM RE, 1996, NEUROL MED CHIR TO S, V43, P26
  • [3] Cerebellopointine angle medulloblastoma
    Jaiswal, AK
    Mahapatra, AK
    Sharma, MC
    [J]. JOURNAL OF CLINICAL NEUROSCIENCE, 2004, 11 (01) : 42 - 45
  • [4] Detection of genetic and chromosomal aberrations in medulloblastomas and primitive neuroectodermal tumors with DNA microarrays
    Kagawa, Naoki
    Maruno, Motohiko
    Suzuki, Tsuyoshi
    Hashiba, Tetsuo
    Hashimoto, Naoya
    Izumoto, Shuichi
    Yoshimine, Toshiki
    [J]. BRAIN TUMOR PATHOLOGY, 2006, 23 (01) : 41 - 47
  • [5] Prediction of central nervous system embryonal tumour outcome based on gene expression
    Pomeroy, SL
    Tamayo, P
    Gaasenbeek, M
    Sturla, LM
    Angelo, M
    McLaughlin, ME
    Kim, JYH
    Goumnerova, LC
    Black, PM
    Lau, C
    Allen, JC
    Zagzag, D
    Olson, JM
    Curran, T
    Wetmore, C
    Biegel, JA
    Poggio, T
    Mukherjee, S
    Rifkin, R
    Califano, A
    Stolovitzky, G
    Louis, DN
    Mesirov, JP
    Lander, ES
    Golub, TR
    [J]. NATURE, 2002, 415 (6870) : 436 - 442
  • [6] Primitive neuroectodermal tumors of the brainstem: Investigation of seven cases
    Zagzag, D
    Miller, DC
    Knopp, E
    Farmer, JP
    Lee, M
    Biria, S
    Pellicer, A
    Epstein, FJ
    Allen, JC
    [J]. PEDIATRICS, 2000, 106 (05) : 1045 - 1053