Stereocontrolled addition of enolates to chiral 2-acyl-1,3-oxathiane derivatives

被引：6

作者：

Matsubara, S ^{[1
]}

Kasuga, Y

Yasui, T

Yoshioka, M

Yamin, B

Utimoto, K

Oshima, K

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Chem Mat, Sakyo Ku, Kyoto 6068501, Japan

[2] Univ Kebangsaan Malaysia, Fac Phys & Appl Sci, Dept Chem, Selangor, Malaysia

来源：

CHIRALITY | 2003年 / 15卷 / 01期

关键词：

enolate; samarium; diastereoselective; aldol;

D O I：

10.1002/chir.10147

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Both enantiomers of 3-hydroxyalkanoates and -alkanones were prepared by the diastereocontrolled addition of enolates to ketones containing (R)-6-methyl-1,3-oxathiane moiety as a chiral auxiliary; a formation of enolate from samarium(II) iodide and alpha-bromoamide is also discussed. (C) 2002 Wiley-Liss, Inc.

引用

页码：38 / 40

页数：3

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