Pharmacological management of posttraumatic stress disorder

被引:16
作者
Bernardy, Nancy C. [1 ,2 ]
Friedman, Matthew J. [1 ,2 ]
机构
[1] Vet Affairs Med Ctr, Natl Ctr Posttraumat Stress Disorder 116D, 215 North Main St, White River Jct, VT 05009 USA
[2] Geisel Sch Med Dartmouth, Dept Psychiat, 1 Rope Ferry Rd, Hanover, NH 03755 USA
关键词
PLACEBO-CONTROLLED TRIAL; COMORBID ALCOHOL DEPENDENCE; PROLONGED EXPOSURE THERAPY; COGNITIVE-BEHAVIORAL THERAPY; RANDOMIZED CONTROLLED-TRIAL; D-CYCLOSERINE; DOUBLE-BLIND; ANXIETY DISORDERS; COMBAT VETERANS; PILOT TRIAL;
D O I
10.1016/j.copsyc.2017.01.003
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Posttraumatic stress disorder (PTSD) has been conceptualized as an inability to cope with overwhelming stress that is followed by a distinctive pattern of symptoms. This concept has made it possible to develop therapeutic approaches for PTSD that include medication and psychotherapy options. In this article we summarize research studies on pharmacotherapies for PTSD and review new findings in the neurobiology of PTSD that are promoting the development of targeted treatment options. Research findings that have improved our understanding of psychobiological abnormalities associated with PTSD offer clinicians improved treatment strategies. We review those findings, the developments in the medication management of PTSD and common co-occurring disorders, and new areas of pharmacological research on PTSD treatment.
引用
收藏
页码:116 / 121
页数:6
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