ADRENAL AXIS IN CRITICAL ILLNESS

被引：0

作者：

Sosa, Soledad ^{[1
]}

Danilowicz, Karina ^{[1
]}

Rizzo, Leonardo F. L. ^{[1
]}

机构：

[1] Univ Buenos Aires, Hosp Clin Jose San Martin, Div Endocrinol, Buenos Aires, DF, Argentina

来源：

MEDICINA-BUENOS AIRES | 2021年 / 81卷 / 01期

关键词：

cortisol; metabolism; adrenal insufficiency; critical illness; CORTICOSTEROID INSUFFICIENCY; CORTISOL METABOLISM; ILL PATIENTS; GLUCOCORTICOID-RECEPTOR; HYDROCORTISONE; MANAGEMENT; FLUDROCORTISONE; CORTICOTROPIN; SUPPRESSION; DIAGNOSIS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

After a stressful event, adaptative mechanisms are carried out to support vital functions. Hypothalamic-pituitary-adrenal axis plays a key role in stress response regulating metabolism, cardiovascular function and immune system. This review addresses pathophysiological changes of the adrenal axis during critical illness, recognizing limitations of methods applied for its evaluation in this special context and defining indications for corticosteroid replacement in critically ill patients. The concept of relative adrenal insufficiency should be abandoned; cosyntropin stimulation test should not be performed for diagnosis of adrenal insufficiency in critical illness nor for establishing the need of treatment.

引用

页码：69 / 75

页数：7

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